Liver cell adenoma with concomitant hepatocellular carcinoma: Report of two cases

Wen Yu Chuang, Tse Ching Chen, Hui-Ling Hsu, Wei Chen Lee, Long Bin Jeng, Shiu Feng Huang

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Malignant transformation of liver cell adenoma and unequivocal hepatocellular carcinoma in resected liver cell adenomas are rare. We report two cases of liver cell adenoma with concomitant hepatocellular carcinoma. The first occurred in a 19-year-old male with asymptomatic liver mass and was discovered incidentally. He had a history of nephrotic syndrome treated with oral prednisolone for 15 years. The second occurred in a 46-year-old female who was admitted due to right tubo-ovarian absces. Computerized tomography scanning incidentally found a 10-cm liver mass in the right lobe. There was no history of oral contraceptive use. Both patients were negative for serum hepatitis B surface antigen and anti-hepatitis C virus antibody. Neither had cirrhosis. These two cases imply that malignant transformation of liver cell adenoma does occur, and that liver cell adenomas should be excised when malignant transformation is suspected.

Original languageEnglish
Pages (from-to)798-802
Number of pages5
JournalJournal of the Formosan Medical Association
Volume101
Issue number11
Publication statusPublished - Nov 1 2002
Externally publishedYes

Keywords

  • Hepatocellular carcinoma
  • Liver cell adenoma
  • Malignant transformation

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Chuang, W. Y., Chen, T. C., Hsu, H-L., Lee, W. C., Jeng, L. B., & Huang, S. F. (2002). Liver cell adenoma with concomitant hepatocellular carcinoma: Report of two cases. Journal of the Formosan Medical Association, 101(11), 798-802.