Lipoblastoma/lipoblastomatosis: A clinicopathologic study of 16 cases in Taiwan

Shih Ming Jung, Pei Yeh Chang, Chih Cheng Luo, Chen Sheng Huang, Jin Yao Lai, Chuen Hsueh

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Abstract

Lipoblastoma/lipoblastomatosis is an uncommon benign lipomatous tumor affecting mainly infants and children. It presents as a painless mass located frequently in upper and lower extremities. The present study was conducted to characterize the clinicopathologic features of lipoblastoma/lipoblastomatosis in a Chinese population. A retrospective survey of 16 cases of pathologically confirmed lipoblastoma/lipoblastomatosis from 1988 to 2002 was performed. The available clinical information and histological sections were reviewed. The study involved 10 males and 6 females ranging in age from 5 to 49 months (median, 11.5 months). The patients presented with mass involving neck (n=5), inguina (n=3), feet (n=2), arm (n=1), leg (n=1), thorax (n=1), mesentery (n=1), buttock (n=1), and presacral region(n=1). The lesions were removed surgically. Histologically, the majority (11/16) of primary tumors were of diffuse type. Follow-up ranging from 5 to 125 months was available in 13 patients. Four patients experienced a recurrence of tumors in the neck (n=2) and lower extremities (n=2) 11-84 months after operation. The most common site of involvement of lipoblastoma/lipoblastomatosis in our series was the neck. A follow-up period of more than 3 years is recommended for patients with this condition.

Original languageEnglish
Pages (from-to)809-812
Number of pages4
JournalPediatric Surgery International
Volume21
Issue number10
DOIs
Publication statusPublished - Oct 2005
Externally publishedYes

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Keywords

  • Adipose tumor
  • Lipoblastoma
  • Lipoblastomatosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Jung, S. M., Chang, P. Y., Luo, C. C., Huang, C. S., Lai, J. Y., & Hsueh, C. (2005). Lipoblastoma/lipoblastomatosis: A clinicopathologic study of 16 cases in Taiwan. Pediatric Surgery International, 21(10), 809-812. https://doi.org/10.1007/s00383-005-1502-x