Lipid metabolism is altered by nebacitin in rats fed cooked-stored polished rice as the only dietary carbohydrate with or without exogenous cholesterol

Hsing Hsien Cheng, Wen Wen Yu

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Male adult Wistar rats were randomly divided into four groups in a 2 x 2 factorial design and were fed diets containing cooked-stored polished rice (CSPR), with and without 0.7 g/100 g of Nebacitin [bacitracinneomycin sulfate (2:1, wt/wt)] and with and without 1 g cholesterol/100 g diet. The CSPR diet contained 1.87 g resistant starch/100 g. After 4 wk, arterial blood and liver were collected. Feces were collected during the last 7 d. Rats fed the diet with Nebacitin and cholesterol had higher serum total cholesterol than the rats fed diets without cholesterol. Serum triglyceride concentration was greater in rats fed Nebacitin, regardless of dietary cholesterol concentration. Rats fed the diet with Nebacitin and cholesterol had higher serum LDL cholesterol concentration and liver total cholesterol concentration than rats fed the other three diets. Rats fed the CSPR diet with Nebacitin both with and without cholesterol had a higher fecal resistant starch concentration and excretion and lower serum short-chain fatty acid concentration than rats fed the diets without Nebacitin. Hepatic cholesterol concentration was greater in rats fed Nebacitin only when the diet also contained cholesterol. Therefore, dietary Nebacitin alters lipid metabolism in rats, and some effects are most pronounced in those also fed cholesterol.

Original languageEnglish
Pages (from-to)153-157
Number of pages5
JournalJournal of Nutrition
Volume127
Issue number1
Publication statusPublished - Jan 1997

Fingerprint

Dietary Carbohydrates
dietary carbohydrate
stored grain
Lipid Metabolism
lipid metabolism
Cholesterol
cholesterol
Diet
rats
diet
blood serum
resistant starch
Serum
Starch
Liver
liver
Nebacetin
Oryza
Dietary Cholesterol
Volatile Fatty Acids

Keywords

  • carbohydrate
  • lipid metabolism
  • nebacitin
  • rats
  • rice

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Lipid metabolism is altered by nebacitin in rats fed cooked-stored polished rice as the only dietary carbohydrate with or without exogenous cholesterol. / Cheng, Hsing Hsien; Yu, Wen Wen.

In: Journal of Nutrition, Vol. 127, No. 1, 01.1997, p. 153-157.

Research output: Contribution to journalArticle

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