Lifetime risk of urothelial carcinoma and lung cancer in the arseniasis-endemic area of Northeastern Taiwan

Tse Yen Yang, Ling I. Hsu, Hui Chi Chen, Hung Yi Chiou, Yu Mei Hsueh, Meei Maan Wu, Chi Ling Chen, Yuan Hung Wang, Ya Tang Liao, Chien Jen Chen

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Arsenic in drinking water has been shown to increase the risk of urothelial carcinoma and lung cancer. However, the lifetime risk of developing urothelial carcinoma and lung cancer caused by exposure to arsenic in drinking water has not been reported. This study aimed to assess the lifetime risk of urothelial carcinoma and lung cancer caused by arsenic exposure from drinking water and cigarette smoking habit for residents living in the arseniasis-endemic area in Northeastern Taiwan. We recruited 8086 residents in 1991-1994 and monitored them for their newly developed types of cancers, identified by computerized linkage with the national cancer registry profile. There were 37 newly diagnosed urothelial carcinoma cases and 223 new lung cancer cases during the follow-up period (until 2007). The lifetime (35-85. years old) cumulative risk of developing urothelial carcinoma from an arsenic concentration in the drinking water of

Original languageEnglish
Pages (from-to)332-337
Number of pages6
JournalJournal of Asian Earth Sciences
Volume77
DOIs
Publication statusPublished - Nov 5 2013

Keywords

  • Arsenic
  • Cigarette smoking
  • Lifetime risk
  • Lung cancer
  • Urothelial carcinoma

ASJC Scopus subject areas

  • Earth-Surface Processes
  • Geology

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