Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging

A case report

Chih Shan Huang, Hao Wen Teng, Sey En Lin, Chia Yuen Chen, Jia Ying Sung

Research output: Contribution to journalArticle

Abstract

Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalActa Neurologica Taiwanica
Volume20
Issue number3
Publication statusPublished - Sep 2011

Fingerprint

Cranial Nerve Diseases
Non-Hodgkin's Lymphoma
Cerebrospinal Fluid
Lymphoma
Central Nervous System
Magnetic Resonance Imaging
Neoplasm Metastasis
Cranial Nerves
Neuroimaging

Keywords

  • Cranial nerve palsy
  • Leptomeningeal metastasis
  • Lymphomatosis
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging : A case report. / Huang, Chih Shan; Teng, Hao Wen; Lin, Sey En; Chen, Chia Yuen; Sung, Jia Ying.

In: Acta Neurologica Taiwanica, Vol. 20, No. 3, 09.2011, p. 192-196.

Research output: Contribution to journalArticle

@article{48f7d40a42054a31a10b964619130ed8,
title = "Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging: A case report",
abstract = "Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.",
keywords = "Cranial nerve palsy, Leptomeningeal metastasis, Lymphomatosis, Non-Hodgkin's lymphoma",
author = "Huang, {Chih Shan} and Teng, {Hao Wen} and Lin, {Sey En} and Chen, {Chia Yuen} and Sung, {Jia Ying}",
year = "2011",
month = "9",
language = "English",
volume = "20",
pages = "192--196",
journal = "Acta Neurologica Taiwanica",
issn = "1019-6099",
publisher = "Taiwan Neurological Society",
number = "3",

}

TY - JOUR

T1 - Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging

T2 - A case report

AU - Huang, Chih Shan

AU - Teng, Hao Wen

AU - Lin, Sey En

AU - Chen, Chia Yuen

AU - Sung, Jia Ying

PY - 2011/9

Y1 - 2011/9

N2 - Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.

AB - Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.

KW - Cranial nerve palsy

KW - Leptomeningeal metastasis

KW - Lymphomatosis

KW - Non-Hodgkin's lymphoma

UR - http://www.scopus.com/inward/record.url?scp=81855180679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=81855180679&partnerID=8YFLogxK

M3 - Article

VL - 20

SP - 192

EP - 196

JO - Acta Neurologica Taiwanica

JF - Acta Neurologica Taiwanica

SN - 1019-6099

IS - 3

ER -