Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging: A case report

Chih Shan Huang, Hao Wen Teng, Sey En Lin, Chia Yuen Chen, Jia Ying Sung

Research output: Contribution to journalArticle

Abstract

Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalActa Neurologica Taiwanica
Volume20
Issue number3
Publication statusPublished - Sep 2011

Keywords

  • Cranial nerve palsy
  • Leptomeningeal metastasis
  • Lymphomatosis
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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