Abstract
Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.
| Original language | English |
|---|---|
| Pages (from-to) | 192-196 |
| Number of pages | 5 |
| Journal | Acta Neurologica Taiwanica |
| Volume | 20 |
| Issue number | 3 |
| Publication status | Published - Sep 2011 |
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Keywords
- Cranial nerve palsy
- Leptomeningeal metastasis
- Lymphomatosis
- Non-Hodgkin's lymphoma
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging : A case report. / Huang, Chih Shan; Teng, Hao Wen; Lin, Sey En; Chen, Chia Yuen; Sung, Jia Ying.
In: Acta Neurologica Taiwanica, Vol. 20, No. 3, 09.2011, p. 192-196.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Leptomeningeal metastasis of malignant lymphoma with negative results in magnetic resonance imaging
T2 - A case report
AU - Huang, Chih Shan
AU - Teng, Hao Wen
AU - Lin, Sey En
AU - Chen, Chia Yuen
AU - Sung, Jia Ying
PY - 2011/9
Y1 - 2011/9
N2 - Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.
AB - Prupose: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. Leptomeningeal metastases may present as multiple cranial nerve involvements. Diagnosis is achieved by recognizing the clinical manifestations, followed by neuroradiologic studies and laboratory examination of the cerebrospinal fluid. But normal studies of either method do not exclude such a diagnosis. Case Report: We present one female patient with non-Hodgkin's lymphoma, who had multiple cranial nerve palsies as signs of central nervous system involvement, but who had negative results in her neuroimaging studies. Conclusion: Patients with multiple cranial nerve palsies should receive cytological examinations of the cerebrospinal fluid in spite of the negative neuroimging results.
KW - Cranial nerve palsy
KW - Leptomeningeal metastasis
KW - Lymphomatosis
KW - Non-Hodgkin's lymphoma
UR - http://www.scopus.com/inward/record.url?scp=81855180679&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81855180679&partnerID=8YFLogxK
M3 - Article
C2 - 22009123
AN - SCOPUS:81855180679
VL - 20
SP - 192
EP - 196
JO - Acta Neurologica Taiwanica
JF - Acta Neurologica Taiwanica
SN - 1019-6099
IS - 3
ER -