Lens position parameters as predictors of intraocular pressure reduction after cataract surgery in nonglaucomatous patients with open angles

Chi Hsin Hsu, Caitlin L. Kakigi, Shuai Chun Lin, Yuan Hung Wang, Travis Porco, Shan C. Lin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

PURPOSE. To evaluate the relationship between lens position parameters and intraocular pressure (IOP) reduction after cataract surgery in nonglaucomatous eyes with open angles. METHODS. The main outcome of the prospective study was percentage of IOP change, which was calculated using the preoperative IOP and the IOP 4 months after cataract surgery in nonglaucomatous eyes with open angles. Lens position (LP), defined as anterior chamber depth (ACD) ± 1/2 lens thickness (LT), was assessed preoperatively using parameters from optical biometry. Preoperative IOP, central corneal thickness, ACD, LT, axial length (AXL), and the ratio of preoperative IOP to ACD (PD ratio) were also evaluated as potential predictors of percentage of IOP change. The predictive values of the parameters we found to be associated with the primary outcome were compared. RESULTS. Four months after cataract surgery, the average IOP reduction was 2.03 ± 2.42 mm Hg, a 12.74% reduction from the preoperative mean of 14.5 6 3.05 mm Hg. Lens position was correlated with IOP reduction percentage after adjusting for confounders (P = 0.002). Higher preoperative IOP, shallower ACD, shorter AXL, and thicker LT were significantly associated with percentage of IOP decrease. Although not statistically significant, LP was a better predictor of percentage of IOP change compared to PD ratio, preoperative IOP, and ACD. CONCLUSIONS. The percentage of IOP reduction after cataract surgery in nonglaucomatous eyes with open angles is greater in more anteriorly positioned lenses. Lens position, which is convenient to compute by basic ocular biometric data, is an accessible predictor with considerable predictive value for postoperative IOP change

Original languageEnglish
Pages (from-to)7807-7813
Number of pages7
JournalInvestigative Ophthalmology and Visual Science
Volume56
Issue number13
DOIs
Publication statusPublished - Dec 1 2015

Fingerprint

Intraocular Pressure
Cataract
Lenses
Anterior Chamber
Biometry

Keywords

  • Cataract surgery
  • Intraocular pressure reduction
  • Lens position parameters
  • Open angles
  • Predictors

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Lens position parameters as predictors of intraocular pressure reduction after cataract surgery in nonglaucomatous patients with open angles. / Hsu, Chi Hsin; Kakigi, Caitlin L.; Lin, Shuai Chun; Wang, Yuan Hung; Porco, Travis; Lin, Shan C.

In: Investigative Ophthalmology and Visual Science, Vol. 56, No. 13, 01.12.2015, p. 7807-7813.

Research output: Contribution to journalArticle

@article{7251f65e990f4af7bd935d0a24d669a3,
title = "Lens position parameters as predictors of intraocular pressure reduction after cataract surgery in nonglaucomatous patients with open angles",
abstract = "PURPOSE. To evaluate the relationship between lens position parameters and intraocular pressure (IOP) reduction after cataract surgery in nonglaucomatous eyes with open angles. METHODS. The main outcome of the prospective study was percentage of IOP change, which was calculated using the preoperative IOP and the IOP 4 months after cataract surgery in nonglaucomatous eyes with open angles. Lens position (LP), defined as anterior chamber depth (ACD) ± 1/2 lens thickness (LT), was assessed preoperatively using parameters from optical biometry. Preoperative IOP, central corneal thickness, ACD, LT, axial length (AXL), and the ratio of preoperative IOP to ACD (PD ratio) were also evaluated as potential predictors of percentage of IOP change. The predictive values of the parameters we found to be associated with the primary outcome were compared. RESULTS. Four months after cataract surgery, the average IOP reduction was 2.03 ± 2.42 mm Hg, a 12.74{\%} reduction from the preoperative mean of 14.5 6 3.05 mm Hg. Lens position was correlated with IOP reduction percentage after adjusting for confounders (P = 0.002). Higher preoperative IOP, shallower ACD, shorter AXL, and thicker LT were significantly associated with percentage of IOP decrease. Although not statistically significant, LP was a better predictor of percentage of IOP change compared to PD ratio, preoperative IOP, and ACD. CONCLUSIONS. The percentage of IOP reduction after cataract surgery in nonglaucomatous eyes with open angles is greater in more anteriorly positioned lenses. Lens position, which is convenient to compute by basic ocular biometric data, is an accessible predictor with considerable predictive value for postoperative IOP change",
keywords = "Cataract surgery, Intraocular pressure reduction, Lens position parameters, Open angles, Predictors",
author = "Hsu, {Chi Hsin} and Kakigi, {Caitlin L.} and Lin, {Shuai Chun} and Wang, {Yuan Hung} and Travis Porco and Lin, {Shan C.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1167/iovs.15-17926",
language = "English",
volume = "56",
pages = "7807--7813",
journal = "Investigative Ophthalmology and Visual Science",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "13",

}

TY - JOUR

T1 - Lens position parameters as predictors of intraocular pressure reduction after cataract surgery in nonglaucomatous patients with open angles

AU - Hsu, Chi Hsin

AU - Kakigi, Caitlin L.

AU - Lin, Shuai Chun

AU - Wang, Yuan Hung

AU - Porco, Travis

AU - Lin, Shan C.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - PURPOSE. To evaluate the relationship between lens position parameters and intraocular pressure (IOP) reduction after cataract surgery in nonglaucomatous eyes with open angles. METHODS. The main outcome of the prospective study was percentage of IOP change, which was calculated using the preoperative IOP and the IOP 4 months after cataract surgery in nonglaucomatous eyes with open angles. Lens position (LP), defined as anterior chamber depth (ACD) ± 1/2 lens thickness (LT), was assessed preoperatively using parameters from optical biometry. Preoperative IOP, central corneal thickness, ACD, LT, axial length (AXL), and the ratio of preoperative IOP to ACD (PD ratio) were also evaluated as potential predictors of percentage of IOP change. The predictive values of the parameters we found to be associated with the primary outcome were compared. RESULTS. Four months after cataract surgery, the average IOP reduction was 2.03 ± 2.42 mm Hg, a 12.74% reduction from the preoperative mean of 14.5 6 3.05 mm Hg. Lens position was correlated with IOP reduction percentage after adjusting for confounders (P = 0.002). Higher preoperative IOP, shallower ACD, shorter AXL, and thicker LT were significantly associated with percentage of IOP decrease. Although not statistically significant, LP was a better predictor of percentage of IOP change compared to PD ratio, preoperative IOP, and ACD. CONCLUSIONS. The percentage of IOP reduction after cataract surgery in nonglaucomatous eyes with open angles is greater in more anteriorly positioned lenses. Lens position, which is convenient to compute by basic ocular biometric data, is an accessible predictor with considerable predictive value for postoperative IOP change

AB - PURPOSE. To evaluate the relationship between lens position parameters and intraocular pressure (IOP) reduction after cataract surgery in nonglaucomatous eyes with open angles. METHODS. The main outcome of the prospective study was percentage of IOP change, which was calculated using the preoperative IOP and the IOP 4 months after cataract surgery in nonglaucomatous eyes with open angles. Lens position (LP), defined as anterior chamber depth (ACD) ± 1/2 lens thickness (LT), was assessed preoperatively using parameters from optical biometry. Preoperative IOP, central corneal thickness, ACD, LT, axial length (AXL), and the ratio of preoperative IOP to ACD (PD ratio) were also evaluated as potential predictors of percentage of IOP change. The predictive values of the parameters we found to be associated with the primary outcome were compared. RESULTS. Four months after cataract surgery, the average IOP reduction was 2.03 ± 2.42 mm Hg, a 12.74% reduction from the preoperative mean of 14.5 6 3.05 mm Hg. Lens position was correlated with IOP reduction percentage after adjusting for confounders (P = 0.002). Higher preoperative IOP, shallower ACD, shorter AXL, and thicker LT were significantly associated with percentage of IOP decrease. Although not statistically significant, LP was a better predictor of percentage of IOP change compared to PD ratio, preoperative IOP, and ACD. CONCLUSIONS. The percentage of IOP reduction after cataract surgery in nonglaucomatous eyes with open angles is greater in more anteriorly positioned lenses. Lens position, which is convenient to compute by basic ocular biometric data, is an accessible predictor with considerable predictive value for postoperative IOP change

KW - Cataract surgery

KW - Intraocular pressure reduction

KW - Lens position parameters

KW - Open angles

KW - Predictors

UR - http://www.scopus.com/inward/record.url?scp=84950336306&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84950336306&partnerID=8YFLogxK

U2 - 10.1167/iovs.15-17926

DO - 10.1167/iovs.15-17926

M3 - Article

AN - SCOPUS:84950336306

VL - 56

SP - 7807

EP - 7813

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

IS - 13

ER -