Lens opacities in young individuals long after exposure to protracted low-dose-rate γ radiation in 60Co-contaminated buildings in Taiwan

Wanhua Annie Hsieh, I. Feng Lin, Wushou P. Chang, Wei Li Chen, Yea H. Hsu, Muh Shy Chen

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25 Citations (Scopus)


The objective of this study was to assess lenticular changes in a young population years after exposure to protracted long-term low-dose-rate γ radiation in Taiwan. A total of 41 males and 32 females who lived for several years in 60Co-contaminated buildings and were less than 20 years old at their first ophthalmological examination in 1998 had a similar examination 4.7 ± 0.5 years later. Lens opacities were examined by slit-lamp biomicroscopy and were scored by the Lens Opacities Classification System III (LOCS III) and a modified subclinical minor focal lens defect (FLD) system. The FLD scores for both eyes were significantly higher than those in the 1998 examinations. Increases in FLD scores compared to those for unexposed subjects occurred particularly in the anterior lens cortex. Increases in FLD scores were also significantly associated with the amount of previous protracted radiation exposure. An exposure-dependent increase in lens opacities was noted years after individuals relocated from the radiocontaminated environment, suggesting that late lenticular changes persisted and progressed in individuals with previous protracted radiation exposure.

Original languageEnglish
Pages (from-to)197-204
Number of pages8
JournalRadiation Research
Issue number2
Publication statusPublished - Feb 2010

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Biophysics
  • Radiation


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