Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure

Pimei Nancy Yen, Chen Chang Yang, Wushou Peter Chang, Jung Der Wang, Jing Shiang Hwang, Tien Chun Chang, Kuan Liang Kuo, I. Feng Lin

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: To evaluate the late effects on the quality of life (QOL) of individual years after protracting low-dose radiation exposure. Materials and methods: We assessed 1,818 subjects using the World Health Organization Questionnaire on Quality of Life-Brief Version (WHOQOL-BREF) in several Health-Related Quality of Life (HRQoL) domains. After adjusting for demographic characteristics and comorbidities, we examined the HRQoL differences at various levels of exposure and ages at disclosure. We also evaluated the potential effect modification by gender. Results: After adjusting for potential confounders, girls aged 12 years or younger at the disclosure of exposure had lower HRQoL scores in physical, psychological, and environmental domains compared to those with later age at disclosure. The differences in the HRQoL scores between different exposure subgroups were not significant in physical, psychological, and social relationship domains, and only appeared in the environmental domain. Conclusions: Being female and less than 12 years of age at disclosure were more significant predictors of HRQoL scores than the levels of radiation exposure among people exposed to protracted low-dose radiation. Further studies are needed to determine the psychological distresses, such as depression and anxiety, and their relationships in this case, especially for the most vulnerable young females.

Original languageEnglish
Pages (from-to)639-644
Number of pages6
JournalInternational Journal of Radiation Biology
Volume89
Issue number8
DOIs
Publication statusPublished - Aug 2013

Fingerprint

Environmental Exposure
Quality of Life
Disclosure
Population
Psychology
Radiation Exposure
Comorbidity
Anxiety
Demography
Radiation
Depression

Keywords

  • Health-related quality of life
  • Late effect
  • Perception risk
  • Prolonged low-dose-rate radiation exposure
  • Taiwan
  • WHOQOL-BREF

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure. / Yen, Pimei Nancy; Yang, Chen Chang; Chang, Wushou Peter; Wang, Jung Der; Hwang, Jing Shiang; Chang, Tien Chun; Kuo, Kuan Liang; Lin, I. Feng.

In: International Journal of Radiation Biology, Vol. 89, No. 8, 08.2013, p. 639-644.

Research output: Contribution to journalArticle

Yen, Pimei Nancy ; Yang, Chen Chang ; Chang, Wushou Peter ; Wang, Jung Der ; Hwang, Jing Shiang ; Chang, Tien Chun ; Kuo, Kuan Liang ; Lin, I. Feng. / Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure. In: International Journal of Radiation Biology. 2013 ; Vol. 89, No. 8. pp. 639-644.
@article{ade027ec8d7d4fd9bf1ee4b5dccbabc5,
title = "Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure",
abstract = "Purpose: To evaluate the late effects on the quality of life (QOL) of individual years after protracting low-dose radiation exposure. Materials and methods: We assessed 1,818 subjects using the World Health Organization Questionnaire on Quality of Life-Brief Version (WHOQOL-BREF) in several Health-Related Quality of Life (HRQoL) domains. After adjusting for demographic characteristics and comorbidities, we examined the HRQoL differences at various levels of exposure and ages at disclosure. We also evaluated the potential effect modification by gender. Results: After adjusting for potential confounders, girls aged 12 years or younger at the disclosure of exposure had lower HRQoL scores in physical, psychological, and environmental domains compared to those with later age at disclosure. The differences in the HRQoL scores between different exposure subgroups were not significant in physical, psychological, and social relationship domains, and only appeared in the environmental domain. Conclusions: Being female and less than 12 years of age at disclosure were more significant predictors of HRQoL scores than the levels of radiation exposure among people exposed to protracted low-dose radiation. Further studies are needed to determine the psychological distresses, such as depression and anxiety, and their relationships in this case, especially for the most vulnerable young females.",
keywords = "Health-related quality of life, Late effect, Perception risk, Prolonged low-dose-rate radiation exposure, Taiwan, WHOQOL-BREF",
author = "Yen, {Pimei Nancy} and Yang, {Chen Chang} and Chang, {Wushou Peter} and Wang, {Jung Der} and Hwang, {Jing Shiang} and Chang, {Tien Chun} and Kuo, {Kuan Liang} and Lin, {I. Feng}",
year = "2013",
month = "8",
doi = "10.3109/09553002.2013.784423",
language = "English",
volume = "89",
pages = "639--644",
journal = "International Journal of Radiation Biology",
issn = "0955-3002",
publisher = "Informa Healthcare",
number = "8",

}

TY - JOUR

T1 - Late effects on the health-related quality of life in a cohort population decades after environmental radiation exposure

AU - Yen, Pimei Nancy

AU - Yang, Chen Chang

AU - Chang, Wushou Peter

AU - Wang, Jung Der

AU - Hwang, Jing Shiang

AU - Chang, Tien Chun

AU - Kuo, Kuan Liang

AU - Lin, I. Feng

PY - 2013/8

Y1 - 2013/8

N2 - Purpose: To evaluate the late effects on the quality of life (QOL) of individual years after protracting low-dose radiation exposure. Materials and methods: We assessed 1,818 subjects using the World Health Organization Questionnaire on Quality of Life-Brief Version (WHOQOL-BREF) in several Health-Related Quality of Life (HRQoL) domains. After adjusting for demographic characteristics and comorbidities, we examined the HRQoL differences at various levels of exposure and ages at disclosure. We also evaluated the potential effect modification by gender. Results: After adjusting for potential confounders, girls aged 12 years or younger at the disclosure of exposure had lower HRQoL scores in physical, psychological, and environmental domains compared to those with later age at disclosure. The differences in the HRQoL scores between different exposure subgroups were not significant in physical, psychological, and social relationship domains, and only appeared in the environmental domain. Conclusions: Being female and less than 12 years of age at disclosure were more significant predictors of HRQoL scores than the levels of radiation exposure among people exposed to protracted low-dose radiation. Further studies are needed to determine the psychological distresses, such as depression and anxiety, and their relationships in this case, especially for the most vulnerable young females.

AB - Purpose: To evaluate the late effects on the quality of life (QOL) of individual years after protracting low-dose radiation exposure. Materials and methods: We assessed 1,818 subjects using the World Health Organization Questionnaire on Quality of Life-Brief Version (WHOQOL-BREF) in several Health-Related Quality of Life (HRQoL) domains. After adjusting for demographic characteristics and comorbidities, we examined the HRQoL differences at various levels of exposure and ages at disclosure. We also evaluated the potential effect modification by gender. Results: After adjusting for potential confounders, girls aged 12 years or younger at the disclosure of exposure had lower HRQoL scores in physical, psychological, and environmental domains compared to those with later age at disclosure. The differences in the HRQoL scores between different exposure subgroups were not significant in physical, psychological, and social relationship domains, and only appeared in the environmental domain. Conclusions: Being female and less than 12 years of age at disclosure were more significant predictors of HRQoL scores than the levels of radiation exposure among people exposed to protracted low-dose radiation. Further studies are needed to determine the psychological distresses, such as depression and anxiety, and their relationships in this case, especially for the most vulnerable young females.

KW - Health-related quality of life

KW - Late effect

KW - Perception risk

KW - Prolonged low-dose-rate radiation exposure

KW - Taiwan

KW - WHOQOL-BREF

UR - http://www.scopus.com/inward/record.url?scp=84881159588&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881159588&partnerID=8YFLogxK

U2 - 10.3109/09553002.2013.784423

DO - 10.3109/09553002.2013.784423

M3 - Article

C2 - 23484866

AN - SCOPUS:84881159588

VL - 89

SP - 639

EP - 644

JO - International Journal of Radiation Biology

JF - International Journal of Radiation Biology

SN - 0955-3002

IS - 8

ER -