Late Cardiovascular Complications After Surgical or Balloon Angioplasty of Coarctation of Aorta in an Asian Cohort

Hsin Hui Chiu, Shuenn Nan Chiu, Fu Chang Hu, Chun An Chen, Ming Tai Lin, Jou Kou Wang, Chung I. Chang, Yih Shang Chen, Ing Sh Chiu, Mei Hwan Wu

Research output: Contribution to journalArticle

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Abstract

Late cardiovascular complications after intervention for coarctation of the aorta (CoA) might be common. Such data, especially in Asian populations, are still limited. A total of 169 patients with CoA who survived balloon (n = 41) or surgical (n = 128) intervention from 1986 to 2004 were enrolled. The total follow-up was 1,776 patient-years, and the patient age at last follow-up was 14.7 ± 8.5 years. Reintervention for recoarctation, systemic hypertension, and left ventricular outflow tract obstruction (LVOTO) was subsequently noted in 57 (34%), 36 (21.3%), and 24 (14.2%) patients, respectively, without significant differences between the balloon and surgical groups. The 20-year freedom from reintervention, systemic hypertension, and LVOTO rate was 52%, 78.6%, and 80.8% in the balloon group and 59%, 51%, and 81.9% in the surgical group, respectively. The age at CoA intervention and the aortic geometry after CoA intervention of gothic type were common risk factors for reintervention for recoarctation and late systemic hypertension. In contrast, the presence of bicuspid aortic valves and gothic arch geometry after CoA intervention increased the risk of LVOTO. Plasma renin/aldosterone activities were not elevated in those with or without systemic hypertension. In conclusion, the profile of reintervention for recoarctation and late systemic hypertension after CoA interventions in our Asian cohort with CoA was similar to that observed in white patients. Asian patients might have a lower risk of LVOTO.

Original languageEnglish
Pages (from-to)1139-1144
Number of pages6
JournalAmerican Journal of Cardiology
Volume104
Issue number8
DOIs
Publication statusPublished - Oct 15 2009
Externally publishedYes

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Aortic Coarctation
Balloon Angioplasty
Ventricular Outflow Obstruction
Hypertension
Aldosterone
Renin
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Late Cardiovascular Complications After Surgical or Balloon Angioplasty of Coarctation of Aorta in an Asian Cohort. / Chiu, Hsin Hui; Chiu, Shuenn Nan; Hu, Fu Chang; Chen, Chun An; Lin, Ming Tai; Wang, Jou Kou; Chang, Chung I.; Chen, Yih Shang; Chiu, Ing Sh; Wu, Mei Hwan.

In: American Journal of Cardiology, Vol. 104, No. 8, 15.10.2009, p. 1139-1144.

Research output: Contribution to journalArticle

Chiu, HH, Chiu, SN, Hu, FC, Chen, CA, Lin, MT, Wang, JK, Chang, CI, Chen, YS, Chiu, IS & Wu, MH 2009, 'Late Cardiovascular Complications After Surgical or Balloon Angioplasty of Coarctation of Aorta in an Asian Cohort', American Journal of Cardiology, vol. 104, no. 8, pp. 1139-1144. https://doi.org/10.1016/j.amjcard.2009.06.009
Chiu, Hsin Hui ; Chiu, Shuenn Nan ; Hu, Fu Chang ; Chen, Chun An ; Lin, Ming Tai ; Wang, Jou Kou ; Chang, Chung I. ; Chen, Yih Shang ; Chiu, Ing Sh ; Wu, Mei Hwan. / Late Cardiovascular Complications After Surgical or Balloon Angioplasty of Coarctation of Aorta in an Asian Cohort. In: American Journal of Cardiology. 2009 ; Vol. 104, No. 8. pp. 1139-1144.
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AU - Chiu, Shuenn Nan

AU - Hu, Fu Chang

AU - Chen, Chun An

AU - Lin, Ming Tai

AU - Wang, Jou Kou

AU - Chang, Chung I.

AU - Chen, Yih Shang

AU - Chiu, Ing Sh

AU - Wu, Mei Hwan

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AB - Late cardiovascular complications after intervention for coarctation of the aorta (CoA) might be common. Such data, especially in Asian populations, are still limited. A total of 169 patients with CoA who survived balloon (n = 41) or surgical (n = 128) intervention from 1986 to 2004 were enrolled. The total follow-up was 1,776 patient-years, and the patient age at last follow-up was 14.7 ± 8.5 years. Reintervention for recoarctation, systemic hypertension, and left ventricular outflow tract obstruction (LVOTO) was subsequently noted in 57 (34%), 36 (21.3%), and 24 (14.2%) patients, respectively, without significant differences between the balloon and surgical groups. The 20-year freedom from reintervention, systemic hypertension, and LVOTO rate was 52%, 78.6%, and 80.8% in the balloon group and 59%, 51%, and 81.9% in the surgical group, respectively. The age at CoA intervention and the aortic geometry after CoA intervention of gothic type were common risk factors for reintervention for recoarctation and late systemic hypertension. In contrast, the presence of bicuspid aortic valves and gothic arch geometry after CoA intervention increased the risk of LVOTO. Plasma renin/aldosterone activities were not elevated in those with or without systemic hypertension. In conclusion, the profile of reintervention for recoarctation and late systemic hypertension after CoA interventions in our Asian cohort with CoA was similar to that observed in white patients. Asian patients might have a lower risk of LVOTO.

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