Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

Chia-Kwung Fan, Yun-Ho Lin, Chien Ching Hung, Kua-Eyre Su

Research output: Contribution to journalArticle

Abstract

Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2% formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.
Original languageEnglish
Pages (from-to)99-105
Number of pages7
Journal臺灣獸醫學雜誌
Volume30
Issue number2
Publication statusPublished - 2004

Fingerprint

Toxocara canis
Eggs
Infection
Pepsin A
Brain
Formaldehyde
Larva
Digestion
Lung
Acids
Liver

Keywords

  • 犬蛔蟲
  • 幼蟲移行行為
  • 小鼠
  • Larval migratory behavior
  • Mice
  • Toxocara canis

Cite this

Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice. / Fan, Chia-Kwung; Lin, Yun-Ho; Hung, Chien Ching; Su, Kua-Eyre.

In: 臺灣獸醫學雜誌, Vol. 30, No. 2, 2004, p. 99-105.

Research output: Contribution to journalArticle

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abstract = "Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2{\%} formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.",
keywords = "犬蛔蟲, 幼蟲移行行為, 小鼠, Larval migratory behavior, Mice, Toxocara canis",
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T1 - Larval Migratory Behavior of Long-term-maintained Toxocara canis Embryonated Eggs in Mice

AU - Fan, Chia-Kwung

AU - Lin, Yun-Ho

AU - Hung, Chien Ching

AU - Su, Kua-Eyre

PY - 2004

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AB - Larval migratory behavior of Toxocara canis embryonated eggs that had been maintained in 2% formalin for 14 months at 4℃ was evaluated using a larval recovery study in mice at between 1 and 469 days post infection (DPI) . Three infected mice and 2 aged-matched uninfected control mice were sacrificed daily for acid-pepsin digestion of the liver and lungs (hepatopulmonary phase) as well as the musculature and brain (myotropic-neurotropic phase). Larval recovery from the hepatopulmonary phase reached a peak at 5 DPI, not at 2 DPI; thereafter, they began to migrate to the myotropic-neurotropic phase. Statistically, larval recoveries from the hepatopulmonary and myotropic-neurotropic phases respectively showed negative and positive correlations with time (r = - 0.688, P = 0.005; r = 0. 138, P = 0.327). Altogether, although there seemed to be a delay in the migration of 14-month-cultured T. canis larvae to the hepatopulmonary phase, most of them still exhibited the myotropic-neurotropic phase, especially in the brain.

KW - 犬蛔蟲

KW - 幼蟲移行行為

KW - 小鼠

KW - Larval migratory behavior

KW - Mice

KW - Toxocara canis

M3 - Article

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SN - 1682-6485

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