Large-Scale Functional Brain Network Reorganization during Taoist Meditation

Tun Jao, Chia Wei Li, Petra E. Vértes, Changwei Wesley Wu, Sophie Achard, Chao Hsien Hsieh, Chien Hui Liou, Jyh Horng Chen, Edward T. Bullmore

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Meditation induces a distinct and reversible mental state that provides insights into brain correlates of consciousness. We explored brain network changes related to meditation by graph theoretical analysis of resting-state functional magnetic resonance imaging data. Eighteen Taoist meditators with varying levels of expertise were scanned using a within-subjects counterbalanced design during resting and meditation states. State-related differences in network topology were measured globally and at the level of individual nodes and edges. Although measures of global network topology, such as small-worldness, were unchanged, meditation was characterized by an extensive and expertise-dependent reorganization of the hubs (highly connected nodes) and edges (functional connections). Areas of sensory cortex, especially the bilateral primary visual and auditory cortices, and the bilateral temporopolar areas, which had the highest degree (or connectivity) during the resting state, showed the biggest decrease during meditation. Conversely, bilateral thalamus and components of the default mode network, mainly the bilateral precuneus and posterior cingulate cortex, had low degree in the resting state but increased degree during meditation. Additionally, these changes in nodal degree were accompanied by reorganization of anatomical orientation of the edges. During meditation, long-distance longitudinal (antero-posterior) edges increased proportionally, whereas orthogonal long-distance transverse (right-left) edges connecting bilaterally homologous cortices decreased. Our findings suggest that transient changes in consciousness associated with meditation introduce convergent changes in the topological and spatial properties of brain functional networks, and the anatomical pattern of integration might be as important as the global level of integration when considering the network basis for human consciousness.

Original languageEnglish
Pages (from-to)9-24
Number of pages16
JournalBrain Connectivity
Volume6
Issue number1
DOIs
Publication statusPublished - Feb 1 2016
Externally publishedYes

Fingerprint

Meditation
Brain
Consciousness
Parietal Lobe
Auditory Cortex
Gyrus Cinguli
Visual Cortex
Thalamus
Magnetic Resonance Imaging

Keywords

  • brain networks
  • consciousness
  • fMRI
  • functional connectivity
  • meditation
  • network hubs
  • resting state

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Jao, T., Li, C. W., Vértes, P. E., Wu, C. W., Achard, S., Hsieh, C. H., ... Bullmore, E. T. (2016). Large-Scale Functional Brain Network Reorganization during Taoist Meditation. Brain Connectivity, 6(1), 9-24. https://doi.org/10.1089/brain.2014.0318

Large-Scale Functional Brain Network Reorganization during Taoist Meditation. / Jao, Tun; Li, Chia Wei; Vértes, Petra E.; Wu, Changwei Wesley; Achard, Sophie; Hsieh, Chao Hsien; Liou, Chien Hui; Chen, Jyh Horng; Bullmore, Edward T.

In: Brain Connectivity, Vol. 6, No. 1, 01.02.2016, p. 9-24.

Research output: Contribution to journalArticle

Jao, T, Li, CW, Vértes, PE, Wu, CW, Achard, S, Hsieh, CH, Liou, CH, Chen, JH & Bullmore, ET 2016, 'Large-Scale Functional Brain Network Reorganization during Taoist Meditation', Brain Connectivity, vol. 6, no. 1, pp. 9-24. https://doi.org/10.1089/brain.2014.0318
Jao, Tun ; Li, Chia Wei ; Vértes, Petra E. ; Wu, Changwei Wesley ; Achard, Sophie ; Hsieh, Chao Hsien ; Liou, Chien Hui ; Chen, Jyh Horng ; Bullmore, Edward T. / Large-Scale Functional Brain Network Reorganization during Taoist Meditation. In: Brain Connectivity. 2016 ; Vol. 6, No. 1. pp. 9-24.
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