Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma

Ma L. Ko; Cherng J. Jeng; Shih Hung Huang; Jenta Shen; Su Chee Chen; Chii Ruey Tzeng

doi:10.1016/S1028-4559(08)60111-4

Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma

Ma L. Ko, Cherng J. Jeng, Shih Hung Huang, Jenta Shen, Su Chee Chen, Chii Ruey Tzeng

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

Original language	English
Pages (from-to)	68-70
Number of pages	3
Journal	Taiwanese Journal of Obstetrics and Gynecology
Volume	46
Issue number	1
DOIs	https://doi.org/10.1016/S1028-4559(08)60111-4
Publication status	Published - Mar 2007
Externally published	Yes

Keywords

Adenocarcinoma of the cervix
Large cell neuroendocrine carcinoma of the cervix

ASJC Scopus subject areas

Obstetrics and Gynaecology

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10.1016/S1028-4559(08)60111-4

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title = "Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma",

abstract = "Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.",

keywords = "Adenocarcinoma of the cervix, Large cell neuroendocrine carcinoma of the cervix",

author = "Ko, {Ma L.} and Jeng, {Cherng J.} and Huang, {Shih Hung} and Jenta Shen and Chen, {Su Chee} and Tzeng, {Chii Ruey}",

year = "2007",

month = mar,

doi = "10.1016/S1028-4559(08)60111-4",

language = "English",

volume = "46",

pages = "68--70",

journal = "Taiwanese Journal of Obstetrics and Gynecology",

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publisher = "臺灣婦產科醫學會",

number = "1",

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TY - JOUR

T1 - Large cell neuroendocrine carcinoma of the uterine cervix associated with adenocarcinoma

AU - Ko, Ma L.

AU - Jeng, Cherng J.

AU - Huang, Shih Hung

AU - Shen, Jenta

AU - Chen, Su Chee

AU - Tzeng, Chii Ruey

PY - 2007/3

Y1 - 2007/3

N2 - Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

AB - Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

KW - Adenocarcinoma of the cervix

KW - Large cell neuroendocrine carcinoma of the cervix

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