Laparoendoscopic single-site adrenalectomy in patients with primary hyperaldosteronism: A prospective study with long-term follow up

Ya Hui Hu, Che Hsiung Wu, Leay Kiaw Er, Chia Da Lin, Ying Buh Liu, Shih Chieh Chueh, Yao Chou Tsai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective Laparoendoscopic single-site (LESS) adrenalectomy is a promising minimally invasive technique, however, the current evidence has not confirmed its long-term effectiveness in primary aldosteronism (PA). We conducted a study to analyze the long-term efficacy of LESS adrenalectomy in patients with PA. Methods A total of 49 patients who had been clinically confirmed with PA who had an indication for unilateral adrenalectomy were included in this study. Perioperative data were obtained for all patients. Blood pressure and the levels of serum aldosterone, renin, and potassium were checked periodically. The median follow-up was 16.5 months. Results No intra- or early post-operative complication occurred. All LESS adrenalectomies were completed successfully, except one with laparoscopic conversion. Hypokalemia was resolved in all cases and no patient required potassium supplements after surgery. Post-operative cure of hypertension was achieved in 63% of our patients. Overall, 84% of our PA patients had clinical improvement in blood pressure control after surgery. Conclusions Our long-term experience revealed that LESS adrenalectomy is a safe and effective approach, which demonstrated comparable long-term cure and improvement of hypertension to a conventional laparoscopic series in treating PA.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalAsian Journal of Surgery
Volume40
Issue number3
DOIs
Publication statusPublished - May 2017
Externally publishedYes

Keywords

  • adrenalectomy
  • laparoendoscopic single-site surgery
  • primary aldosteronism

ASJC Scopus subject areas

  • Surgery

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