Labdane diterpenoid glycosides from Alpinia densespicata and their nitric oxide inhibitory activities in macrophages

Yu Jen Kuo, Ping Chun Hsiao, Li Jie Zhang, Ming Der Wu, Yu Han Liang, Hsiu O. Ho, Yao Haur Kuo

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Four new labdane diterpene glycosides (1-4) named alpindenosides A, B, C, and D, two new norditerpene glycosides (5, 6) named noralpindenosides A and B, and three known flavonoid glycosides (7-9) have been isolated from the stems of Alpinia densespicata. Structural elucidation of compounds 1-6 was based on spectroscopic data. Compounds 1-9 all exhibited moderate NO inhibitory activities, whereas they were noncytotoxic at 20 μ M against several human tumor cell lines.

Original languageEnglish
Pages (from-to)1097-1101
Number of pages5
JournalJournal of Natural Products
Volume72
Issue number6
DOIs
Publication statusPublished - Jun 26 2009

ASJC Scopus subject areas

  • Complementary and alternative medicine
  • Molecular Medicine
  • Organic Chemistry
  • Analytical Chemistry
  • Pharmaceutical Science
  • Pharmacology
  • Drug Discovery

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