Knowledge, satisfaction, and concerns regarding warfarin therapy and their association with warfarin adherence and anticoagulation control

Ye Wang, Ming Chai Kong, Lai Heng Lee, Heng Joo Ng, Yu Ko

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Introduction A better understanding of patients' knowledge, satisfaction and concerns can identify deficits and help develop targeted patient education. This study aimed to examine patients' knowledge, satisfaction and concerns regarding warfarin therapy and assess their association with warfarin adherence and international normalized ratio (INR) control. Materials and methods A cross-sectional survey was conducted in a convenience sample of patients taking warfarin in an anticoagulation clinic. The questionnaire consisted of questions on patients' knowledge, satisfaction and concerns regarding warfarin treatment. Patients' warfarin refill records and time within the therapeutic INR range were retrieved from hospital databases. Results One hundred and eighty-three patients participated in the survey. Patients had inadequate knowledge of warfarin-diet and warfarin-drug interactions. Over 40% of the respondents were not satisfied with the waiting time to see a pharmacist. The most common concerns of taking warfarin were worries about warfarin-drug interactions (36.1%), forgetting to take warfarin (26.2%) and worries about side effects (25.7%). Higher satisfaction was associated with better knowledge (r = 0.24, p = 0.001) and fewer concerns (rs = - 0.23, p = 0.002). Better knowledge and higher satisfaction were associated with higher warfarin adherence (r s = 0.21 and 0.16; p = 0.01 and 0.046, respectively). Better knowledge, higher satisfaction, fewer concerns, and better warfarin adherence were associated with good INR control (p = 0.003, 0.02, 0.03 and 0.003, respectively). Conclusions This study highlighted patients' concerns and deficits in knowledge regarding warfarin treatment, and also demonstrated their association with warfarin adherence and INR control.

Original languageEnglish
Pages (from-to)550-554
Number of pages5
JournalThrombosis Research
Volume133
Issue number4
DOIs
Publication statusPublished - 2014
Externally publishedYes

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Warfarin
International Normalized Ratio
Therapeutics
Patient Satisfaction
Drug Interactions
Patient Education
Pharmacists
Cross-Sectional Studies

Keywords

  • Anticoagulant
  • Concerns
  • Knowledge
  • Medication adherence
  • Satisfaction
  • Warfarin

ASJC Scopus subject areas

  • Hematology
  • Medicine(all)

Cite this

Knowledge, satisfaction, and concerns regarding warfarin therapy and their association with warfarin adherence and anticoagulation control. / Wang, Ye; Kong, Ming Chai; Lee, Lai Heng; Ng, Heng Joo; Ko, Yu.

In: Thrombosis Research, Vol. 133, No. 4, 2014, p. 550-554.

Research output: Contribution to journalArticle

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AU - Ko, Yu

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N2 - Introduction A better understanding of patients' knowledge, satisfaction and concerns can identify deficits and help develop targeted patient education. This study aimed to examine patients' knowledge, satisfaction and concerns regarding warfarin therapy and assess their association with warfarin adherence and international normalized ratio (INR) control. Materials and methods A cross-sectional survey was conducted in a convenience sample of patients taking warfarin in an anticoagulation clinic. The questionnaire consisted of questions on patients' knowledge, satisfaction and concerns regarding warfarin treatment. Patients' warfarin refill records and time within the therapeutic INR range were retrieved from hospital databases. Results One hundred and eighty-three patients participated in the survey. Patients had inadequate knowledge of warfarin-diet and warfarin-drug interactions. Over 40% of the respondents were not satisfied with the waiting time to see a pharmacist. The most common concerns of taking warfarin were worries about warfarin-drug interactions (36.1%), forgetting to take warfarin (26.2%) and worries about side effects (25.7%). Higher satisfaction was associated with better knowledge (r = 0.24, p = 0.001) and fewer concerns (rs = - 0.23, p = 0.002). Better knowledge and higher satisfaction were associated with higher warfarin adherence (r s = 0.21 and 0.16; p = 0.01 and 0.046, respectively). Better knowledge, higher satisfaction, fewer concerns, and better warfarin adherence were associated with good INR control (p = 0.003, 0.02, 0.03 and 0.003, respectively). Conclusions This study highlighted patients' concerns and deficits in knowledge regarding warfarin treatment, and also demonstrated their association with warfarin adherence and INR control.

AB - Introduction A better understanding of patients' knowledge, satisfaction and concerns can identify deficits and help develop targeted patient education. This study aimed to examine patients' knowledge, satisfaction and concerns regarding warfarin therapy and assess their association with warfarin adherence and international normalized ratio (INR) control. Materials and methods A cross-sectional survey was conducted in a convenience sample of patients taking warfarin in an anticoagulation clinic. The questionnaire consisted of questions on patients' knowledge, satisfaction and concerns regarding warfarin treatment. Patients' warfarin refill records and time within the therapeutic INR range were retrieved from hospital databases. Results One hundred and eighty-three patients participated in the survey. Patients had inadequate knowledge of warfarin-diet and warfarin-drug interactions. Over 40% of the respondents were not satisfied with the waiting time to see a pharmacist. The most common concerns of taking warfarin were worries about warfarin-drug interactions (36.1%), forgetting to take warfarin (26.2%) and worries about side effects (25.7%). Higher satisfaction was associated with better knowledge (r = 0.24, p = 0.001) and fewer concerns (rs = - 0.23, p = 0.002). Better knowledge and higher satisfaction were associated with higher warfarin adherence (r s = 0.21 and 0.16; p = 0.01 and 0.046, respectively). Better knowledge, higher satisfaction, fewer concerns, and better warfarin adherence were associated with good INR control (p = 0.003, 0.02, 0.03 and 0.003, respectively). Conclusions This study highlighted patients' concerns and deficits in knowledge regarding warfarin treatment, and also demonstrated their association with warfarin adherence and INR control.

KW - Anticoagulant

KW - Concerns

KW - Knowledge

KW - Medication adherence

KW - Satisfaction

KW - Warfarin

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