Kimura's disease with generalized lymphadenopathy demonstrated by positron emission tomography scan

Tso Fu Wang, Shu Hsin Liu, Chih Hao K. Kao, Sung Chao Chu, Ruey Ho Kao, Chi Cheng Li

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Kimura's disease is a chronic inflammatory disorder that occurs mainly in Asian patients. Most imaging studies focus on the loco-regional involvement of this disorder. Images of the whole body fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET) scan have not been reported in the literature before. The possibility of lymphoid clonality is also discussed frequently despite its clinically benign course. We present a patient of Kimura's disease initially assessed by whole body 18F-FDG PET study and proved by pathologic findings. 18F-FDG-PET scan showed diffusely intense uptake in the neck, axillary, pelvic and inguinal nodal regions bilaterally, as well as in the mediastinal, celiac region. The flow cytometric analysis of lymph node tissue confirmed the absence of clonality. The image of 18F-FDG-PET in Kimura's disease can closely resemble that seen in neoplastic disorders such as lymphoma or metastatic lymphadenopathy. It should be taken into consideration as a differential diagnosis for a generalized lymphadenopathy

Original languageEnglish
Pages (from-to)775-778
Number of pages4
JournalInternal Medicine
Volume45
Issue number12
DOIs
Publication statusPublished - Jul 18 2006
Externally publishedYes

Keywords

  • Clonality
  • Flowcytometry
  • Generalized lymphadenopathy
  • Kimura's disease
  • Positron emission tomography

ASJC Scopus subject areas

  • Internal Medicine

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