Kawasaki disease: An update on diagnosis and treatment

Ho Chang Kuo, Kuender D. Yang, Wei Chiao Chang, Luo Ping Ger, Kai Sheng Hsieh

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology occurring mostly in infants and children younger than 5 years of age. In developed countries, it is the leading cause of acquired heart disease in children. However, KD remains a mysterious disease. Some viruses potentially causing the condition have been isolated, but the results have not been able to be reproduced. This article reviews and summarizes different aspects of KD and provides updated information on diagnosis and treatment. The supplementary criteria for incomplete presentation of KD patients suggested by the American Heart Association, treatment (including tumor necrosis factor-alpha antagonist, methylprednisolone pulse therapy, statins, plasma exchange, and cytotoxic agents) for those with intravenous immunoglobulin treatment failure, and other experiences are also included in this review.

Original languageEnglish
Pages (from-to)4-11
Number of pages8
JournalPediatrics and Neonatology
Volume53
Issue number1
DOIs
Publication statusPublished - Feb 2012
Externally publishedYes

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Mucocutaneous Lymph Node Syndrome
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Plasma Exchange
Intravenous Immunoglobulins
Cytotoxins
Methylprednisolone
Therapeutics
Vasculitis
Treatment Failure
Developed Countries
Heart Diseases
Tumor Necrosis Factor-alpha
Viruses

Keywords

  • coronary artery lesion
  • IVIG
  • Kawasaki disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Kawasaki disease : An update on diagnosis and treatment. / Kuo, Ho Chang; Yang, Kuender D.; Chang, Wei Chiao; Ger, Luo Ping; Hsieh, Kai Sheng.

In: Pediatrics and Neonatology, Vol. 53, No. 1, 02.2012, p. 4-11.

Research output: Contribution to journalArticle

Kuo, Ho Chang ; Yang, Kuender D. ; Chang, Wei Chiao ; Ger, Luo Ping ; Hsieh, Kai Sheng. / Kawasaki disease : An update on diagnosis and treatment. In: Pediatrics and Neonatology. 2012 ; Vol. 53, No. 1. pp. 4-11.
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