Justicia lignans: Part 10-Synthesis of tiruneesiin, the first neolignan from Justicia species

Gottumukkala V. Subbaraju, Jakka Kavitha, Dodda Rajasekhar, Feng L. Hsu, Kur T. Cheng

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

(±)-Tiruneesiin, 3-[2-(4-hydroxy-3-methoxyphenyl)-3-acetoxymethyl-7- methoxy-2, 3-dihydro-1-benzofuran-5-yl]propan-1-yl acetate 1, is synthesized starting from methyl ferulate 2 with an overall yield of 12.6%. Ag2O induced dimerization of 2 is used as a key step in the synthesis.

Original languageEnglish
Pages (from-to)357-359
Number of pages3
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume46
Issue number2
Publication statusPublished - Feb 2007

Keywords

  • Justicia neesii
  • Neolignan
  • Oxidative dimerization
  • Synthesis
  • Tiruneesiin

ASJC Scopus subject areas

  • Organic Chemistry

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