Is Acute Lobar Nephronia the Midpoint in the Spectrum of Upper Urinary Tract Infections between Acute Pyelonephritis and Renal Abscess?

Chi Hui Cheng, Yong Kwei Tsau, Tzou Yien Lin

Research output: Contribution to journalArticle

19 Citations (Scopus)


Objective: To examine acute lobar nephronia (ALN) in the spectrum of upper urinary tract infections between acute pyelonephritis (APN) and renal abscess. Study design: Medical records of 115 patients diagnosed with APN, ALN, or renal abscess with computed tomography (CT) were reviewed retrospectively. CT lesions and patterns of ALN were checked, and the volume of CT lesions was estimated in every patient. Then the correlation between clinical presentation and CT lesions was examined. Results: The study included 21 patients with APN, 85 with ALN (63 simple ALN, 22 complicated ALN), and 9 with renal abscesses. The volume fraction of CT lesions correlated well with duration of fever before and after treatment in patients with APN or simple ALN, and only the correlation between fever duration after treatment and CT lesions was significant in patients with complicated ALN or renal abscess. Conclusions: We suggest that simple ALN be regarded clinically as the progression of APN. By contrast, complicated ALN is a distinct, more severe disease entity, and it may relate to or progress to renal abscess. ALN is probably not the midpoint in the traditional dynamic spectrum of upper urinary tract infections between APN and renal abscess.

Original languageEnglish
Pages (from-to)82-86
Number of pages5
JournalJournal of Pediatrics
Issue number1
Publication statusPublished - Jan 2010
Externally publishedYes


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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