Investigation of DNA sequencing droplet trajectory observation and analysis

Jian Chiun Liou, Cheng Fu Yang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this study, DNA sequencing droplet trajectories are observed and analyzed using an application-specific integrated circuit system and a micro-electromechanical system structure jetting chip. We investigate a droplet jetting technique and apply it to biomedical test chips. This use of a sprayed chip structure can reduce sequencing time by two-thirds compared with traditional methods. The structure is a three-dimensional, multi-channel drive system that can control droplets more precisely. The circuit's input control signal was generated and placed on a chip based on the quantitative design of liquid droplets. Delay time and frequency were used to set the LED light sources. In this study, we would use frequencies of 4 kHz, 8 kHz, and 12 kHz combined with two groups of different orifices and frequencies for ink droplet outlet velocity.

Original languageEnglish
Pages (from-to)243-250
Number of pages8
JournalMicroelectronics Reliability
Volume91
DOIs
Publication statusPublished - Dec 1 2018

Fingerprint

sequencing
DNA
deoxyribonucleic acid
chips
Trajectories
trajectories
application specific integrated circuits
orifices
inks
outlets
microelectromechanical systems
Application specific integrated circuits
light sources
Orifices
light emitting diodes
time lag
Ink
MEMS
Light emitting diodes
Light sources

Keywords

  • DNA gene
  • Jets matrix
  • Micro-droplet
  • Multidimensional drive

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Safety, Risk, Reliability and Quality
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Electrical and Electronic Engineering

Cite this

Investigation of DNA sequencing droplet trajectory observation and analysis. / Liou, Jian Chiun; Yang, Cheng Fu.

In: Microelectronics Reliability, Vol. 91, 01.12.2018, p. 243-250.

Research output: Contribution to journalArticle

@article{acec061e9df44f63925fb3238b81e746,
title = "Investigation of DNA sequencing droplet trajectory observation and analysis",
abstract = "In this study, DNA sequencing droplet trajectories are observed and analyzed using an application-specific integrated circuit system and a micro-electromechanical system structure jetting chip. We investigate a droplet jetting technique and apply it to biomedical test chips. This use of a sprayed chip structure can reduce sequencing time by two-thirds compared with traditional methods. The structure is a three-dimensional, multi-channel drive system that can control droplets more precisely. The circuit's input control signal was generated and placed on a chip based on the quantitative design of liquid droplets. Delay time and frequency were used to set the LED light sources. In this study, we would use frequencies of 4 kHz, 8 kHz, and 12 kHz combined with two groups of different orifices and frequencies for ink droplet outlet velocity.",
keywords = "DNA gene, Jets matrix, Micro-droplet, Multidimensional drive",
author = "Liou, {Jian Chiun} and Yang, {Cheng Fu}",
year = "2018",
month = "12",
day = "1",
doi = "10.1016/j.microrel.2018.10.012",
language = "English",
volume = "91",
pages = "243--250",
journal = "Microelectronics and Reliability",
issn = "0026-2714",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Investigation of DNA sequencing droplet trajectory observation and analysis

AU - Liou, Jian Chiun

AU - Yang, Cheng Fu

PY - 2018/12/1

Y1 - 2018/12/1

N2 - In this study, DNA sequencing droplet trajectories are observed and analyzed using an application-specific integrated circuit system and a micro-electromechanical system structure jetting chip. We investigate a droplet jetting technique and apply it to biomedical test chips. This use of a sprayed chip structure can reduce sequencing time by two-thirds compared with traditional methods. The structure is a three-dimensional, multi-channel drive system that can control droplets more precisely. The circuit's input control signal was generated and placed on a chip based on the quantitative design of liquid droplets. Delay time and frequency were used to set the LED light sources. In this study, we would use frequencies of 4 kHz, 8 kHz, and 12 kHz combined with two groups of different orifices and frequencies for ink droplet outlet velocity.

AB - In this study, DNA sequencing droplet trajectories are observed and analyzed using an application-specific integrated circuit system and a micro-electromechanical system structure jetting chip. We investigate a droplet jetting technique and apply it to biomedical test chips. This use of a sprayed chip structure can reduce sequencing time by two-thirds compared with traditional methods. The structure is a three-dimensional, multi-channel drive system that can control droplets more precisely. The circuit's input control signal was generated and placed on a chip based on the quantitative design of liquid droplets. Delay time and frequency were used to set the LED light sources. In this study, we would use frequencies of 4 kHz, 8 kHz, and 12 kHz combined with two groups of different orifices and frequencies for ink droplet outlet velocity.

KW - DNA gene

KW - Jets matrix

KW - Micro-droplet

KW - Multidimensional drive

UR - http://www.scopus.com/inward/record.url?scp=85055294784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055294784&partnerID=8YFLogxK

U2 - 10.1016/j.microrel.2018.10.012

DO - 10.1016/j.microrel.2018.10.012

M3 - Article

AN - SCOPUS:85055294784

VL - 91

SP - 243

EP - 250

JO - Microelectronics and Reliability

JF - Microelectronics and Reliability

SN - 0026-2714

ER -