Inverse correlation between heart rate recovery and metabolic risks in healthy children and adolescents

Lian Yu Lin, Hsu Ko Kuo, Ling Ping Lai, Jiunn Lee Lin, Chuen Den Tseng, Juey Jen Hwang

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

OBJECTIVE - Heart rate recovery (HRR) is a marker for survival. Little is known about the association between HRR and metabolic risks in healthy children or adolescents. RESEARCH DESIGN AND METHODS - We examined 993 healthy children and adolescents aged 12-19 years with reliable measures of cardiovascular fitness from the National Health and Nutrition Examination Survey 1999-2002. HRR parameters 1-3 min after exercise were calculated from exercise test results. Anthropometric and metabolic risk factors as well as metabolic Z score were obtained. RESULTS - The HRR parameters were inversely correlated with most of the metabolic risks, including waist circumference, systolic blood pressure (SBP), serum triglycerides, and serum C-reactive protein (CRP) levels, and were positively correlated with serum HDL levels. In multiple linear regression analysis, among the metabolic risks, waist circumference was the only parameter associated with HRR parameters (P = 0.038, 0.001, and 0.001 for 1-, 2-, and 3-min HRR, respectively) in boys. In girls, waist circumference (P = 0.001 and < 0.001 for 2- and 3-min HRR, respectively), SBP (P = 0.029 for 1-min HRR), serum glucose (P = 0.021 for 2-min HRR), and serum CRP (P = 0.007 for 2-min HRR) levels were the most important determinants of HRR parameters. The adjusted 1-min HRR did not change across four quartiles of metabolic Z score, while the adjusted 3-min HRR decreased significantly with four quartiles of metabolic Z score. CONCLUSIONS - Metabolic risks are inversely associated with HRR in healthy children and adolescents. Our finding suggests that there is a link between metabolic risks and autonomic nervous system functions in healthy young ages.

Original languageEnglish
Pages (from-to)1015-1020
Number of pages6
JournalDiabetes Care
Volume31
Issue number5
DOIs
Publication statusPublished - May 1 2008
Externally publishedYes

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Heart Rate
Waist Circumference
Blood Pressure
C-Reactive Protein
Blood Proteins
Serum
Nutrition Surveys
Autonomic Nervous System
Exercise Test
Linear Models
Triglycerides
Research Design
Regression Analysis
Exercise
Glucose
Survival

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialised Nursing

Cite this

Inverse correlation between heart rate recovery and metabolic risks in healthy children and adolescents. / Lin, Lian Yu; Kuo, Hsu Ko; Lai, Ling Ping; Lin, Jiunn Lee; Tseng, Chuen Den; Hwang, Juey Jen.

In: Diabetes Care, Vol. 31, No. 5, 01.05.2008, p. 1015-1020.

Research output: Contribution to journalArticle

Lin, Lian Yu ; Kuo, Hsu Ko ; Lai, Ling Ping ; Lin, Jiunn Lee ; Tseng, Chuen Den ; Hwang, Juey Jen. / Inverse correlation between heart rate recovery and metabolic risks in healthy children and adolescents. In: Diabetes Care. 2008 ; Vol. 31, No. 5. pp. 1015-1020.
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abstract = "OBJECTIVE - Heart rate recovery (HRR) is a marker for survival. Little is known about the association between HRR and metabolic risks in healthy children or adolescents. RESEARCH DESIGN AND METHODS - We examined 993 healthy children and adolescents aged 12-19 years with reliable measures of cardiovascular fitness from the National Health and Nutrition Examination Survey 1999-2002. HRR parameters 1-3 min after exercise were calculated from exercise test results. Anthropometric and metabolic risk factors as well as metabolic Z score were obtained. RESULTS - The HRR parameters were inversely correlated with most of the metabolic risks, including waist circumference, systolic blood pressure (SBP), serum triglycerides, and serum C-reactive protein (CRP) levels, and were positively correlated with serum HDL levels. In multiple linear regression analysis, among the metabolic risks, waist circumference was the only parameter associated with HRR parameters (P = 0.038, 0.001, and 0.001 for 1-, 2-, and 3-min HRR, respectively) in boys. In girls, waist circumference (P = 0.001 and < 0.001 for 2- and 3-min HRR, respectively), SBP (P = 0.029 for 1-min HRR), serum glucose (P = 0.021 for 2-min HRR), and serum CRP (P = 0.007 for 2-min HRR) levels were the most important determinants of HRR parameters. The adjusted 1-min HRR did not change across four quartiles of metabolic Z score, while the adjusted 3-min HRR decreased significantly with four quartiles of metabolic Z score. CONCLUSIONS - Metabolic risks are inversely associated with HRR in healthy children and adolescents. Our finding suggests that there is a link between metabolic risks and autonomic nervous system functions in healthy young ages.",
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AU - Hwang, Juey Jen

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N2 - OBJECTIVE - Heart rate recovery (HRR) is a marker for survival. Little is known about the association between HRR and metabolic risks in healthy children or adolescents. RESEARCH DESIGN AND METHODS - We examined 993 healthy children and adolescents aged 12-19 years with reliable measures of cardiovascular fitness from the National Health and Nutrition Examination Survey 1999-2002. HRR parameters 1-3 min after exercise were calculated from exercise test results. Anthropometric and metabolic risk factors as well as metabolic Z score were obtained. RESULTS - The HRR parameters were inversely correlated with most of the metabolic risks, including waist circumference, systolic blood pressure (SBP), serum triglycerides, and serum C-reactive protein (CRP) levels, and were positively correlated with serum HDL levels. In multiple linear regression analysis, among the metabolic risks, waist circumference was the only parameter associated with HRR parameters (P = 0.038, 0.001, and 0.001 for 1-, 2-, and 3-min HRR, respectively) in boys. In girls, waist circumference (P = 0.001 and < 0.001 for 2- and 3-min HRR, respectively), SBP (P = 0.029 for 1-min HRR), serum glucose (P = 0.021 for 2-min HRR), and serum CRP (P = 0.007 for 2-min HRR) levels were the most important determinants of HRR parameters. The adjusted 1-min HRR did not change across four quartiles of metabolic Z score, while the adjusted 3-min HRR decreased significantly with four quartiles of metabolic Z score. CONCLUSIONS - Metabolic risks are inversely associated with HRR in healthy children and adolescents. Our finding suggests that there is a link between metabolic risks and autonomic nervous system functions in healthy young ages.

AB - OBJECTIVE - Heart rate recovery (HRR) is a marker for survival. Little is known about the association between HRR and metabolic risks in healthy children or adolescents. RESEARCH DESIGN AND METHODS - We examined 993 healthy children and adolescents aged 12-19 years with reliable measures of cardiovascular fitness from the National Health and Nutrition Examination Survey 1999-2002. HRR parameters 1-3 min after exercise were calculated from exercise test results. Anthropometric and metabolic risk factors as well as metabolic Z score were obtained. RESULTS - The HRR parameters were inversely correlated with most of the metabolic risks, including waist circumference, systolic blood pressure (SBP), serum triglycerides, and serum C-reactive protein (CRP) levels, and were positively correlated with serum HDL levels. In multiple linear regression analysis, among the metabolic risks, waist circumference was the only parameter associated with HRR parameters (P = 0.038, 0.001, and 0.001 for 1-, 2-, and 3-min HRR, respectively) in boys. In girls, waist circumference (P = 0.001 and < 0.001 for 2- and 3-min HRR, respectively), SBP (P = 0.029 for 1-min HRR), serum glucose (P = 0.021 for 2-min HRR), and serum CRP (P = 0.007 for 2-min HRR) levels were the most important determinants of HRR parameters. The adjusted 1-min HRR did not change across four quartiles of metabolic Z score, while the adjusted 3-min HRR decreased significantly with four quartiles of metabolic Z score. CONCLUSIONS - Metabolic risks are inversely associated with HRR in healthy children and adolescents. Our finding suggests that there is a link between metabolic risks and autonomic nervous system functions in healthy young ages.

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