Intrathecal meperidine attenuates shivering induced by spinal anesthesia

J. C. Chen, S. W. Hsu, L. H. Hu, Y. J. Hong, P. S. Tsai, T. C. Lin, C. F. Lin, T. T. Wei

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Shivering is a common and complex phenomenon that occurs in many patients during spinal anesthesia. Shivering can increase oxygen consumption up to 500 per cent which may be detrimental to patients with decreased myocardial reserve. The metabolic costs and cardiorespiratory consequences of shivering are important particularly for patients with anemia, coronary arterial disease, cardiopulmonary insufficient, debilitated status or are elderly. We studied whether intrathecal meperidine could prevent shivering after spinal anesthesia. 60 patients with ASA class I-II were divided into intrathecal meperidine group (Group I) (n = 30) and control group (Group II) (n = 30). Group I received spinal tetracaine 12-16 mg with meperidine 0.2 mg/kg and Group II received spinal tetracaine 12-16 mg without meperidine. During operation the highest level of spinal anesthesia, ambient and rectal temperatures, blood pressure (BP) and heart rate (HR), presence or absence of shivering, intensity of shivering in both groups were recorded. Close observation for side effects was given post-operatively. There was a significant reduction (p < .005) in incidence of shivering in group I patients (16.7%) when compared with group II (56.7%). There was no or less side effects observed with other neuraxial opioids except nausea. We concluded that intrathecal meperidine could suppress shivering induced by spinal anesthesia.

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalMa zui xue za zhi = Anaesthesiologica Sinica
Issue number1
Publication statusPublished - Mar 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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