Intraoperative measurement of fractional flow reserve in off-pump coronary artery bypass: A pilot study

Kuan Ming Chiu, Tzu Yu Lin, Jer Shen Chen, Jih Hsin Huang, Robert Jeen Chen Chen, Shu Hsun Chu

Research output: Contribution to journalArticle

Abstract

Backgrounds Fractional flow reserve of myocardium (FFRmyo) is a functional study of significant coronary artery stenosis, defined as the ratio of the pressure distal to the stenosis (poststenosis) divided by the pressure of aortic root (prestenosis). Instead of cath laboratory, we could measure it in operating room for off-pump coronary artery bypass (OPCAB) surgery and here shared our methods in the pilot study. Methods and Results We used needles, catheters, and pressure tracing but without guidewires or fluoroscopy to measure FFRmyo during OPCAB. In February 2010, we conducted the pilot study and collected 32 anastomosis data from 10 patients. Without revising the anastomosis plans based on coronary angiographies, 24 FFRmyo of the 32 anastomoses (75%) were less than 0.75, which represented significant functional stenosis. The FFRmyo measurements did not lead to any adverse events. Conclusion The measurement of fractional flow reserve in OPCAB is safe and feasible. It can serve as a functional assessment of coronary artery stenosis in adjuvant to conventional coronary angiography.

Original languageEnglish
Pages (from-to)288-291
Number of pages4
JournalThoracic and Cardiovascular Surgeon
Volume63
Issue number4
DOIs
Publication statusPublished - Jul 17 2014
Externally publishedYes

Fingerprint

Off-Pump Coronary Artery Bypass
Myocardium
Coronary Stenosis
Coronary Angiography
Pathologic Constriction
Pressure
Fluoroscopy
Operating Rooms
Coronary Artery Bypass
Needles
Arterial Pressure
Catheters

Keywords

  • fractional flow reserve
  • myocardial revascularization
  • off-pump coronary artery bypass

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Intraoperative measurement of fractional flow reserve in off-pump coronary artery bypass : A pilot study. / Chiu, Kuan Ming; Lin, Tzu Yu; Chen, Jer Shen; Huang, Jih Hsin; Chen, Robert Jeen Chen; Chu, Shu Hsun.

In: Thoracic and Cardiovascular Surgeon, Vol. 63, No. 4, 17.07.2014, p. 288-291.

Research output: Contribution to journalArticle

Chiu, Kuan Ming ; Lin, Tzu Yu ; Chen, Jer Shen ; Huang, Jih Hsin ; Chen, Robert Jeen Chen ; Chu, Shu Hsun. / Intraoperative measurement of fractional flow reserve in off-pump coronary artery bypass : A pilot study. In: Thoracic and Cardiovascular Surgeon. 2014 ; Vol. 63, No. 4. pp. 288-291.
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AB - Backgrounds Fractional flow reserve of myocardium (FFRmyo) is a functional study of significant coronary artery stenosis, defined as the ratio of the pressure distal to the stenosis (poststenosis) divided by the pressure of aortic root (prestenosis). Instead of cath laboratory, we could measure it in operating room for off-pump coronary artery bypass (OPCAB) surgery and here shared our methods in the pilot study. Methods and Results We used needles, catheters, and pressure tracing but without guidewires or fluoroscopy to measure FFRmyo during OPCAB. In February 2010, we conducted the pilot study and collected 32 anastomosis data from 10 patients. Without revising the anastomosis plans based on coronary angiographies, 24 FFRmyo of the 32 anastomoses (75%) were less than 0.75, which represented significant functional stenosis. The FFRmyo measurements did not lead to any adverse events. Conclusion The measurement of fractional flow reserve in OPCAB is safe and feasible. It can serve as a functional assessment of coronary artery stenosis in adjuvant to conventional coronary angiography.

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