Intense pulsed light for the treatment of refractory melasma in Asian persons

Chia Chen Wang, Chung Y. Hui, Yuh M. Sue, Wen R. Wong, Hong Shang Hong

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

BACKGROUND. Patients with dermal or mixed-type melasmas are often refractory to various treatments. Intense pulsed light has been used to treat melanocytic lesions with promising results. OBJECTIVE. The purpose of this study was to clarify the effectiveness of intense pulsed light for refractory melasma in Asian persons. METHODS. Seventeen patients were treated with intense pulsed light, during four sessions at 4-week intervals. The patients were also given 4% hydroquinone cream and broad-spectrum sunscreens to prevent and treat postinflammatory hyperpigmentation. Sixteen patients in the control group were treated with hydroquinone cream and sunscreens. The treatment efficacy was evaluated using reflectance spectrophotometer and patient satisfaction questionnaire. RESULTS. Patients in the intense pulsed light group achieved an average of 39.8% improvement in relative melanin index, compared to 11.6% improvement in the control group (p

Original languageEnglish
Pages (from-to)1196-1200
Number of pages5
JournalDermatologic Surgery
Volume30
Issue number9
DOIs
Publication statusPublished - Sep 2004

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Melanosis
Light
Sunscreening Agents
Therapeutics
Control Groups
Hyperpigmentation
Melanins
Patient Satisfaction
Skin

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

Intense pulsed light for the treatment of refractory melasma in Asian persons. / Wang, Chia Chen; Hui, Chung Y.; Sue, Yuh M.; Wong, Wen R.; Hong, Hong Shang.

In: Dermatologic Surgery, Vol. 30, No. 9, 09.2004, p. 1196-1200.

Research output: Contribution to journalArticle

Wang, Chia Chen ; Hui, Chung Y. ; Sue, Yuh M. ; Wong, Wen R. ; Hong, Hong Shang. / Intense pulsed light for the treatment of refractory melasma in Asian persons. In: Dermatologic Surgery. 2004 ; Vol. 30, No. 9. pp. 1196-1200.
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