Abstract
Background & objectives: Lowering the diagnostic threshold of normal fasting plasma glucose (FPG) from 6.1 to 5.56 mmol/l has been proposed by American Diabetes Association. As early detection of subjects with risk of diabetes is important, it is crucial to understand the relationship between different levels of FPG, insulin resistance (IR) and insulin secretion. We measured IR and insulin secretion in subjects with different levels of FPG to investigate the relationship between FPG and IR and insulin secretion, and to see whether lowering the cut-off improves the sensitivity of impaired fasting glucose to predict diabetes. Methods: Apparently healthy subjects (294) were enrolled and divided into 3 groups according to their FPG levels; group 1 (
Original language | English |
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Pages (from-to) | 527-534 |
Number of pages | 8 |
Journal | Indian Journal of Medical Research |
Volume | 124 |
Publication status | Published - Nov 2006 |
Externally published | Yes |
Keywords
- Fasting plasma glucose
- Insulin resistance
- Insulin secretion
- Insulin suppression test
- Insulinogenic index
- Metabolic syndrome
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)