Ingested inorganic arsenic, cigarettes smoking and risk of urinary cancer in Taiwan

Chi Ling Chen, Hung Yi Chiou, Chien Jen Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our previous studies using data from either southwestern or northeastern arseniasis endemic areas from Taiwan consistently demonstrated an increased risk of urinary cancer, especially urothelial carcinoma, in a dose-response fashion. We conducted analyses to elucidate whether these is an interaction between cigarette smoking and long term arsenic exposure using the information from residents in arseniasis endemic area in northeastern Taiwan. With an average of 12 years follow-up, there were 45 incident urinary cancer cases. The interaction term between arsenic concentration and cigarette smoking status was significant for urinary cancer (p = 0.0222), but not for urothelial carcinoma (p = 0.1085). When combining arsenic concentration and pack-years of cigarettes smoking, the highest relative risk were those who were exposed to $100 μg/L of arsenic and smoked

Original languageEnglish
Title of host publicationUnderstanding the Geological and Medical Interface of Arsenic, As 2012 - 4th International Congress: Arsenic in the Environment
Pages148-150
Number of pages3
Publication statusPublished - 2012
Event4th International Congress on Arsenic in the Environment, As 2012 - Cairns, QLD, Australia
Duration: Jul 22 2012Jul 27 2012

Other

Other4th International Congress on Arsenic in the Environment, As 2012
CountryAustralia
CityCairns, QLD
Period7/22/127/27/12

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ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution

Cite this

Chen, C. L., Chiou, H. Y., & Chen, C. J. (2012). Ingested inorganic arsenic, cigarettes smoking and risk of urinary cancer in Taiwan. In Understanding the Geological and Medical Interface of Arsenic, As 2012 - 4th International Congress: Arsenic in the Environment (pp. 148-150)