Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly

Chen-Ling Huang, Phung Anh Nguyen, Pih lian Kuo, Usman Iqbal, Yi Hsin Elsa Hsu, Wen Shan Jian

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95% CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD.

Original languageEnglish
Pages (from-to)507-511
Number of pages5
JournalComputer Methods and Programs in Biomedicine
Volume111
Issue number2
DOIs
Publication statusPublished - Aug 2013

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Risk Reduction Behavior
Chronic Obstructive Pulmonary Disease
Human Influenza
Myocardial Ischemia
Vaccination
Health insurance
Lung
Vaccines
Influenza Vaccines
National Health Programs
Taiwan
Cause of Death
Databases
Research

Keywords

  • Cohort research database
  • COPD (chronic obstructive pulmonary disease)
  • IHD (ischemic heart disease)
  • Influenza vaccine
  • Vaccination

ASJC Scopus subject areas

  • Computer Science Applications
  • Software
  • Health Informatics

Cite this

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title = "Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly",
abstract = "COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95{\%} CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD.",
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AU - Huang, Chen-Ling

AU - Nguyen, Phung Anh

AU - Kuo, Pih lian

AU - Iqbal, Usman

AU - Hsu, Yi Hsin Elsa

AU - Jian, Wen Shan

PY - 2013/8

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N2 - COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95% CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD.

AB - COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95% CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD.

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KW - IHD (ischemic heart disease)

KW - Influenza vaccine

KW - Vaccination

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