Inflammatory Dietary Pattern Predicts Dyslipidemia and Anemia in Middle-Aged and Older Taiwanese Adults with Declined Kidney Function: A Cross-Sectional Population Study from 2008 to 2010

Adi Lukas Kurniawan, Chien Yeh Hsu, Hsiao Hsien Rau, Li Yin Lin, Jane C.J. Chao

Research output: Contribution to journalArticle

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Abstract

Dyslipidemia, anemia, and inflammation are associated with declined kidney function. This study investigated the association of inflammatory dietary pattern with dyslipidemia, anemia, and kidney function biomarkers among middle-aged and older Taiwanese adults with declined kidney function. Biochemical data and food frequency questionnaire were obtained from 41,128 participants with estimated glomerular filtration rate (eGFR) <90 mL/min/1.73 m2 and positive urinary protein. Inflammatory dietary pattern was identified by reduced rank regression with C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (N/L) as response variables. Males had higher prevalence of dyslipidemia and higher inflammatory markers, but lower prevalence of anemia and lower eGFR levels compared to females. Inflammatory dietary pattern characterized with low intakes of seafood, grains, vegetables, and fruits but high intakes of meat, eggs, preserved/processed foods, and sugary drinks was associated with an increased risk of dyslipidemia by 21% in males and an increased risk of anemia by 28-47% in both genders. Furthermore, high consumption of inflammatory dietary pattern was associated with reduced eGFR (males β = -0.85, 95% CI -1.26 to -0.43, females β = -0.53, 95% CI -0.98 to -0.08) and increased N/L and/or CRP in both genders. In conclusion, inflammatory dietary pattern is positively associated with dyslipidemia, anemia, and decreased kidney function in middle-aged and older adults with declined kidney function.

Original languageEnglish
JournalNutrients
Volume11
Issue number9
DOIs
Publication statusPublished - Sep 2 2019

Fingerprint

middle-aged adults
hyperlipidemia
renal function
Dyslipidemias
eating habits
anemia
Anemia
Cross-Sectional Studies
glomerular filtration rate
Kidney
Glomerular Filtration Rate
Population
C-reactive protein
C-Reactive Protein
Preserved Food
Seafood
meat consumption
gender
food frequency questionnaires
processed foods

Keywords

  • anemia
  • dietary pattern
  • dyslipidemia
  • inflammation
  • kidney function
  • reduced rank regression

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

Cite this

Inflammatory Dietary Pattern Predicts Dyslipidemia and Anemia in Middle-Aged and Older Taiwanese Adults with Declined Kidney Function : A Cross-Sectional Population Study from 2008 to 2010. / Kurniawan, Adi Lukas; Hsu, Chien Yeh; Rau, Hsiao Hsien; Lin, Li Yin; Chao, Jane C.J.

In: Nutrients, Vol. 11, No. 9, 02.09.2019.

Research output: Contribution to journalArticle

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abstract = "Dyslipidemia, anemia, and inflammation are associated with declined kidney function. This study investigated the association of inflammatory dietary pattern with dyslipidemia, anemia, and kidney function biomarkers among middle-aged and older Taiwanese adults with declined kidney function. Biochemical data and food frequency questionnaire were obtained from 41,128 participants with estimated glomerular filtration rate (eGFR) <90 mL/min/1.73 m2 and positive urinary protein. Inflammatory dietary pattern was identified by reduced rank regression with C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (N/L) as response variables. Males had higher prevalence of dyslipidemia and higher inflammatory markers, but lower prevalence of anemia and lower eGFR levels compared to females. Inflammatory dietary pattern characterized with low intakes of seafood, grains, vegetables, and fruits but high intakes of meat, eggs, preserved/processed foods, and sugary drinks was associated with an increased risk of dyslipidemia by 21{\%} in males and an increased risk of anemia by 28-47{\%} in both genders. Furthermore, high consumption of inflammatory dietary pattern was associated with reduced eGFR (males β = -0.85, 95{\%} CI -1.26 to -0.43, females β = -0.53, 95{\%} CI -0.98 to -0.08) and increased N/L and/or CRP in both genders. In conclusion, inflammatory dietary pattern is positively associated with dyslipidemia, anemia, and decreased kidney function in middle-aged and older adults with declined kidney function.",
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