Infective endocarditis in patients with liver cirrhosis

Ron Bin Hsu, Robert J. Chen, Shu Hsun Chun

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17 Citations (Scopus)

Abstract

Background and Purpose: Infective endocarditis complicating liver cirrhosis is infrequently reported. This study evaluated the clinical features of infective endocarditis in Taiwanese patients with liver cirrhosis. Methods: All cases of infective endocarditis occurring in patients with liver cirrhosis from December 1995 to December 2002 were included in this study. Data were collected by restrospective chart review. Results: Twenty six patients (18 males; 8 females) with median age 6 years (range, 43 to 87) were included. The etiology of liver cirrhosis was hepatitis virus infect on in 20 patients. There were 7 nosocomial infections. Bacterial pathogens were identified in 25 patients, with Staphylococcus aureus (n = 8), viridans streptococci (n = 4), Streptococcus sanguis (n=2), Pseudomonas aeruginosa (n = 2), and Enterococcus faecalis (n = 2) the most common isolates. The hospital mortality rate was 27%. Patients with in-hospital death were more likely to have a history of uremia, staphylococcal infection, nosocomial infection and less likely to have aortic valve infection. Conclusions: The prognosis of patients with infective endocarditis and liver cirrhosis was poor. Infection with Staphylococcus species was a dominant cause and methicillin resistance was common.

Original languageEnglish
Pages (from-to)355-358
Number of pages4
JournalJournal of the Formosan Medical Association
Volume103
Issue number5
Publication statusPublished - May 1 2004
Externally publishedYes

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Keywords

  • Bacterial
  • Endocarditis
  • Liver cirrhosis
  • Retrospective studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hsu, R. B., Chen, R. J., & Chun, S. H. (2004). Infective endocarditis in patients with liver cirrhosis. Journal of the Formosan Medical Association, 103(5), 355-358.