Infected cephalohematoma associated with sepsis and skull osteomyelitis: Report of one case

Hsiu Chun Kao, Yhu Chering Huang, Tzou Yien Lin

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20 Citations (Scopus)


Osteomyelitis is rarely complicated by an infected cephalohematoma. We report a case of an infected cephalohematoma associated with Escherichia coli sepsis and osteomyelitis of the skull. This 37-day-old boy had E. coli sepsis, which had a poor response to antibiotic treatment. An infected cephalohematoma was found when he was 43 days old. Cranial computed tomography (CT) scanning showed cephalohematoma with abscess formation and underlying bony destruction over the left parietal region. Antibiotics alone could not eradicate the infection. Extensive incision, drainage, and debridement of the necrotic bone resulted in prompt improvement. Three weeks of ceftizoxime administered intravenously, followed by 3 weeks of cefixime given orally completed the treatment course.

Original languageEnglish
Pages (from-to)459-462
Number of pages4
JournalAmerican Journal of Perinatology
Issue number9
Publication statusPublished - 1999
Externally publishedYes



  • Cephalohematoma
  • Escherichia coli
  • Osteomyelitis
  • Sepsis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

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