Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis

Agriculture & Biology

• Glehnia littoralis 99%
• inducible nitric oxide synthase 70%
• carrageenan 65%
• prostaglandin synthase 63%
• anti-inflammatory activity 60%
• edema 41%
• lipopolysaccharides 31%
• macrophages 21%
• neutrophils 15%
• mice 14%
• Western blotting 13%
• protein synthesis 12%
• injection 11%
• tumor necrosis factors 10%
• indomethacin 8%
• intraperitoneal injection 8%
• glutathione peroxidase 7%
• prostaglandins 7%
• malondialdehyde 7%
• inflammation 7%
• catalase 6%
• superoxide dismutase 6%
• testing 3%
• cells 2%

Medicine & Life Sciences

• imperatorin 100%
• Apiaceae 90%
• Nitric Oxide Synthase Type II 59%
• Cyclooxygenase 2 59%
• Carrageenan 47%
• Anti-Inflammatory Agents 41%
• Edema 23%
• Lipopolysaccharides 19%
• Neutrophil Infiltration 12%
• Macrophages 11%
• Western Blotting 7%
• RAW 264.7 Cells 7%
• Injections 6%
• Glutathione Peroxidase 5%
• Indomethacin 5%
• Intraperitoneal Injections 5%
• Malondialdehyde 5%
• Dinoprostone 5%
• Catalase 5%
• Superoxide Dismutase 5%
• Proteins 4%
• Tumor Necrosis Factor-alpha 4%
• Inflammation 3%
• Serum 2%
• In Vitro Techniques 2%
• Therapeutics 0%

Chemical Compounds

• Imperatorin 93%
• Antiinflammatory 54%
• Carrageenan 28%
• Western Blotting 14%
• Lipopolysaccharide 12%
• Prostaglandin E2 7%
• Intraperitoneal 7%
• Superoxide 5%
• Glutathione 5%
• Peroxidase 5%
• Protein 4%