Indigenous Wildlife Rabies in Taiwan

Ferret Badgers, a Long Term Terrestrial Reservoir

Yu Ching Lan, Tzai Hung Wen, Chao Chin Chang, Hsin Fu Liu, Pei Fen Lee, Chung Yuan Huang, Bruno B. Chomel, Yi Ming A. Chen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The emerging disease of rabies was confirmed in Taiwan ferret badgers (FBs) and reported to the World Organization for Animal Health (OIE) on July 17, 2013. The spread of wildlife rabies can be related to neighborhood countries in Asia. The phylogenetic analysis was conducted by maximum likelihood (ML) methods and the Bayesian coalescent approach based on the glycoprotein (G) and nucleoprotein (N) genes. The phylogeographic and spatial temporal dynamics of viral transmission were determined by using SPREAD, QGIS. Therefore, the origin and the change with time of the viruses can be identified. Results showed the rabies virus of FB strains in Taiwan is a unique clade among other strains in Asia. According to the phylogeographic coalescent tree, three major genotypes of the FB rabies virus have circulated in three different geographical areas in Taiwan. Two genotypes have distributed into central and southern Taiwan between two ecological river barriers. The third genotype has been limited in southeastern Taiwan by the natural mountain barrier. The diversity of FB rabies viruses indicates that the biological profile of FBs could vary in different geographical areas in Taiwan. An enhanced surveillance system needs to be established near the currently identified natural barriers for early warnings of the rabies virus outbreak in Taiwan.

Original languageEnglish
Article number5491640
JournalBioMed Research International
Volume2017
DOIs
Publication statusPublished - Jan 1 2017
Externally publishedYes

Fingerprint

Mustelidae
Ferrets
Rabies
Taiwan
Viruses
Rabies virus
Genotype
Nucleoproteins
Maximum likelihood
Bayes Theorem
Glycoproteins
Animals
Genes
Rivers
Health
Disease Outbreaks

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Indigenous Wildlife Rabies in Taiwan : Ferret Badgers, a Long Term Terrestrial Reservoir. / Lan, Yu Ching; Wen, Tzai Hung; Chang, Chao Chin; Liu, Hsin Fu; Lee, Pei Fen; Huang, Chung Yuan; Chomel, Bruno B.; Chen, Yi Ming A.

In: BioMed Research International, Vol. 2017, 5491640, 01.01.2017.

Research output: Contribution to journalArticle

Lan, Yu Ching ; Wen, Tzai Hung ; Chang, Chao Chin ; Liu, Hsin Fu ; Lee, Pei Fen ; Huang, Chung Yuan ; Chomel, Bruno B. ; Chen, Yi Ming A. / Indigenous Wildlife Rabies in Taiwan : Ferret Badgers, a Long Term Terrestrial Reservoir. In: BioMed Research International. 2017 ; Vol. 2017.
@article{c9435a532a104baa88d01dae5bfd4362,
title = "Indigenous Wildlife Rabies in Taiwan: Ferret Badgers, a Long Term Terrestrial Reservoir",
abstract = "The emerging disease of rabies was confirmed in Taiwan ferret badgers (FBs) and reported to the World Organization for Animal Health (OIE) on July 17, 2013. The spread of wildlife rabies can be related to neighborhood countries in Asia. The phylogenetic analysis was conducted by maximum likelihood (ML) methods and the Bayesian coalescent approach based on the glycoprotein (G) and nucleoprotein (N) genes. The phylogeographic and spatial temporal dynamics of viral transmission were determined by using SPREAD, QGIS. Therefore, the origin and the change with time of the viruses can be identified. Results showed the rabies virus of FB strains in Taiwan is a unique clade among other strains in Asia. According to the phylogeographic coalescent tree, three major genotypes of the FB rabies virus have circulated in three different geographical areas in Taiwan. Two genotypes have distributed into central and southern Taiwan between two ecological river barriers. The third genotype has been limited in southeastern Taiwan by the natural mountain barrier. The diversity of FB rabies viruses indicates that the biological profile of FBs could vary in different geographical areas in Taiwan. An enhanced surveillance system needs to be established near the currently identified natural barriers for early warnings of the rabies virus outbreak in Taiwan.",
author = "Lan, {Yu Ching} and Wen, {Tzai Hung} and Chang, {Chao Chin} and Liu, {Hsin Fu} and Lee, {Pei Fen} and Huang, {Chung Yuan} and Chomel, {Bruno B.} and Chen, {Yi Ming A.}",
year = "2017",
month = "1",
day = "1",
doi = "10.1155/2017/5491640",
language = "English",
volume = "2017",
journal = "BioMed Research International",
issn = "2314-6133",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Indigenous Wildlife Rabies in Taiwan

T2 - Ferret Badgers, a Long Term Terrestrial Reservoir

AU - Lan, Yu Ching

AU - Wen, Tzai Hung

AU - Chang, Chao Chin

AU - Liu, Hsin Fu

AU - Lee, Pei Fen

AU - Huang, Chung Yuan

AU - Chomel, Bruno B.

AU - Chen, Yi Ming A.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - The emerging disease of rabies was confirmed in Taiwan ferret badgers (FBs) and reported to the World Organization for Animal Health (OIE) on July 17, 2013. The spread of wildlife rabies can be related to neighborhood countries in Asia. The phylogenetic analysis was conducted by maximum likelihood (ML) methods and the Bayesian coalescent approach based on the glycoprotein (G) and nucleoprotein (N) genes. The phylogeographic and spatial temporal dynamics of viral transmission were determined by using SPREAD, QGIS. Therefore, the origin and the change with time of the viruses can be identified. Results showed the rabies virus of FB strains in Taiwan is a unique clade among other strains in Asia. According to the phylogeographic coalescent tree, three major genotypes of the FB rabies virus have circulated in three different geographical areas in Taiwan. Two genotypes have distributed into central and southern Taiwan between two ecological river barriers. The third genotype has been limited in southeastern Taiwan by the natural mountain barrier. The diversity of FB rabies viruses indicates that the biological profile of FBs could vary in different geographical areas in Taiwan. An enhanced surveillance system needs to be established near the currently identified natural barriers for early warnings of the rabies virus outbreak in Taiwan.

AB - The emerging disease of rabies was confirmed in Taiwan ferret badgers (FBs) and reported to the World Organization for Animal Health (OIE) on July 17, 2013. The spread of wildlife rabies can be related to neighborhood countries in Asia. The phylogenetic analysis was conducted by maximum likelihood (ML) methods and the Bayesian coalescent approach based on the glycoprotein (G) and nucleoprotein (N) genes. The phylogeographic and spatial temporal dynamics of viral transmission were determined by using SPREAD, QGIS. Therefore, the origin and the change with time of the viruses can be identified. Results showed the rabies virus of FB strains in Taiwan is a unique clade among other strains in Asia. According to the phylogeographic coalescent tree, three major genotypes of the FB rabies virus have circulated in three different geographical areas in Taiwan. Two genotypes have distributed into central and southern Taiwan between two ecological river barriers. The third genotype has been limited in southeastern Taiwan by the natural mountain barrier. The diversity of FB rabies viruses indicates that the biological profile of FBs could vary in different geographical areas in Taiwan. An enhanced surveillance system needs to be established near the currently identified natural barriers for early warnings of the rabies virus outbreak in Taiwan.

UR - http://www.scopus.com/inward/record.url?scp=85018846550&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85018846550&partnerID=8YFLogxK

U2 - 10.1155/2017/5491640

DO - 10.1155/2017/5491640

M3 - Article

VL - 2017

JO - BioMed Research International

JF - BioMed Research International

SN - 2314-6133

M1 - 5491640

ER -