Increased sympathetic nervous system activity in Chinese hypertensive patients with type II diabetes mellitus

Paul Chan, C. W. Wang, T. S. Lin, C. W. Tsai, W. H. Pan

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

To evaluate the coexistence of sympathetic overactivity and hypertension in type 2 diabetic patients, a population-based study was conducted of newly-diagnosed type 2 diabetic patients recruited from a single community located at northern Taiwan. This study included 2877 (male 1382, female 1495) middle-aged ethnic Chinese adults, aged 45-65 years. Of the 1382 males, 67 had newly-diagnosed type 2 diabetes mellitus, whereas 75 of the 1495 females had type 2 diabetes. The data showed that about 39% of diabetic patients had borderline hypertension (mean blood pressure 141/91 mmHg) whereas the average incidence in non-diabetic subjects was 15.5%. The borderline hypertensive diabetic patients had significantly higher heart rates (mean 78.8 vs. 69.3 beats/min; P <0.001) than control subjects. However, the cardiac index was similar in both control and diabetic subjects (mean 2.48 vs. 2.53 l/min/m2; P > 0.05). Our data show that sympathetic overactivity and increased incidence of hypertension actually existed in these type 2 diabetic patients of Chinese origin.

Original languageEnglish
Pages (from-to)69-74
Number of pages6
JournalInternational Journal of Cardiology
Volume50
Issue number1
DOIs
Publication statusPublished - Jun 2 1995
Externally publishedYes

Keywords

  • Coronary artery disease
  • Hypertension
  • Risk factor
  • Sympathetic overactivity
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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