Increased risk of stroke in patients with bullous pemphigoid: A population-based follow-up study

Ya-Wen Yang, Yi Hua Chen, Sudha Xirasagar, Herng Ching Lin

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)

Abstract

Background and Purpose- Although previous research reveals that cardiovascular events and thromboembolic diseases are important causes of death in patients with bullous pemphigoid (BP), the risk of stroke after the diagnosis of BP relative to the general population remains unknown. Using a randomly selected nationwide population-based sample, this study investigates the risk of stroke in patients with BP compared with unaffected individuals of a similar age. Methods- This study analyzes data from Taiwans National Health Insurance Research Database. This sample included 390 patients with BP and 1950 matched subjects as a comparison group. Stratified Cox proportional hazard regressions were used to calculate the 3-year stroke risk for these 2 groups after adjusting for patients age, sex, and comorbid medical disorders at baseline. Results- Of the 2340 patients in the sample, 312 patients (13.3%) had strokes during the 3-year follow-up period, 89 (22.8% of the patients with BP) in the study group and 223 (11.4% of patients without BP) in the comparison group (P

Original languageEnglish
Pages (from-to)319-323
Number of pages5
JournalStroke
Volume42
Issue number2
DOIs
Publication statusPublished - Feb 2011

Keywords

  • bullous pemphigoid
  • epidemiology
  • stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing

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