Increased risk of diabetes following perianal abscess: A population-based follow-up study

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Abstract

Purpose: It remains unclear whether perianal abscess is a prediabetes condition or the initial presentation of type 2 diabetes. Using a population-based dataset, this study aimed to explore the risk of type 2 diabetes following perianal abscess. Methods: We used data sourced from the Longitudinal Health Insurance Database 2000. In total, there were 1,419 adult patients with perianal abscess in the study group and 7,095 randomly selected subjects in the comparison group. Stratified Cox proportional hazards regressions were carried out to evaluate the association between being diagnosed with perianal abscess and receiving a subsequent diagnosis of diabetes within 5 years. Results: Of the total 8,514 sampled subjects, the incidence rate of diabetes per 100 person-years was 1.87 (95 % confidence interval (CI) = 1.74-2.01); the rate among patients with perianal abscess was 3.00 (95 % CI = 2.60-3.43) and was 1.65 (95 % CI = 1.52-1.79) among comparison patients. Stratified Cox proportional hazards analysis revealed that patients with perianal abscess were more likely to have received a diagnosis of diabetes than comparison patients (hazard ratio = 1.80, 95 % CI = 1.50-2.16, p <0.001) during the 5-year follow-up period after censoring cases that died from nondiabetes causes and adjusting for patient geographic location, urbanization level, monthly income, hypertension, coronary heart disease, hyperlipidemia, obesity, and alcohol abuse/alcohol dependence syndrome at baseline. Conclusions: Our results suggest that patients with perianal abscess have a higher chance of contracting type 2 diabetes mellitus within the first 5 years following their diagnosis.

Original languageEnglish
Pages (from-to)235-240
Number of pages6
JournalInternational Journal of Colorectal Disease
Volume28
Issue number2
DOIs
Publication statusPublished - Feb 2013

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Abscess
Population
Confidence Intervals
Type 2 Diabetes Mellitus
Alcoholism
Prediabetic State
Geographic Locations
Urbanization
Health Insurance
Hyperlipidemias
Coronary Disease
Obesity
Databases
Hypertension
Incidence

Keywords

  • Diabetes
  • Diabetes mellitus
  • Perianal abscess

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Increased risk of diabetes following perianal abscess : A population-based follow-up study. / Wei, Po-Li; Keller, Joseph J.; Kuo, Li-Jen; Lin, Herng-Ching.

In: International Journal of Colorectal Disease, Vol. 28, No. 2, 02.2013, p. 235-240.

Research output: Contribution to journalArticle

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abstract = "Purpose: It remains unclear whether perianal abscess is a prediabetes condition or the initial presentation of type 2 diabetes. Using a population-based dataset, this study aimed to explore the risk of type 2 diabetes following perianal abscess. Methods: We used data sourced from the Longitudinal Health Insurance Database 2000. In total, there were 1,419 adult patients with perianal abscess in the study group and 7,095 randomly selected subjects in the comparison group. Stratified Cox proportional hazards regressions were carried out to evaluate the association between being diagnosed with perianal abscess and receiving a subsequent diagnosis of diabetes within 5 years. Results: Of the total 8,514 sampled subjects, the incidence rate of diabetes per 100 person-years was 1.87 (95 {\%} confidence interval (CI) = 1.74-2.01); the rate among patients with perianal abscess was 3.00 (95 {\%} CI = 2.60-3.43) and was 1.65 (95 {\%} CI = 1.52-1.79) among comparison patients. Stratified Cox proportional hazards analysis revealed that patients with perianal abscess were more likely to have received a diagnosis of diabetes than comparison patients (hazard ratio = 1.80, 95 {\%} CI = 1.50-2.16, p <0.001) during the 5-year follow-up period after censoring cases that died from nondiabetes causes and adjusting for patient geographic location, urbanization level, monthly income, hypertension, coronary heart disease, hyperlipidemia, obesity, and alcohol abuse/alcohol dependence syndrome at baseline. Conclusions: Our results suggest that patients with perianal abscess have a higher chance of contracting type 2 diabetes mellitus within the first 5 years following their diagnosis.",
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