Increased risk of adverse pregnancy outcomes for women with migraines: A nationwide population-based study

H. M. Chen, S. F. Chen, Y. H. Chen, H. C. Lin

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Using a 3-year nationwide population-based database, this study aims to examine the risk of adverse pregnancy outcomes in women with migraines, including low birthweight (LBW), preterm birth, infants born small for gestational age, Caesarean section (CS) and pre-eclampsia. We identified a total of 4911 women with migraines who gave birth from 2001 to 2003, together with 24 555 matched women as a comparison cohort. Multivariate logistic regression analyses showed that after adjusting for potential confounders, the odds ratios were 1.16 [95% confidence intervals (CI) = 1.03-1.31, P= 0.014] for LBW, 1.24 (95% CI = 1.13-1.39, P<0.001) for preterm births, 1.16 (95% CI = 1.07-1.24, P <0.001) for CS and 1.34 (95% CI = 1.02-1.77, P = 0.027) for pre-eclampsia for women with migraines compared with unaffected mothers. We conclude that women with migraines were at increased risk of having LBW, preterm babies, pre-eclampsia and delivery by CS, compared with unaffected mothers.

Original languageEnglish
Pages (from-to)433-438
Number of pages6
JournalCephalalgia
Volume30
Issue number4
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Pregnancy Outcome
Migraine Disorders
Pre-Eclampsia
Cesarean Section
Confidence Intervals
Population
Premature Birth
Mothers
Premature Infants
Gestational Age
Logistic Models
Odds Ratio
Regression Analysis
Parturition
Databases

Keywords

  • Migraine
  • Pre-eclampsia
  • Pregnancy complications
  • Preterm birth

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Increased risk of adverse pregnancy outcomes for women with migraines : A nationwide population-based study. / Chen, H. M.; Chen, S. F.; Chen, Y. H.; Lin, H. C.

In: Cephalalgia, Vol. 30, No. 4, 04.2010, p. 433-438.

Research output: Contribution to journalArticle

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