Abstract
Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.
| Original language | English |
|---|---|
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 203 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2010 |
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Keywords
- adverse pregnancy outcome
- herpangina
- pregnancy outcome
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Increased risk of adverse pregnancy outcomes among women affected by herpangina. / Chen, Yi Hua; Lin, Hsiu Chen; Lin, Herng Ching.
In: American Journal of Obstetrics and Gynecology, Vol. 203, No. 1, 07.2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Increased risk of adverse pregnancy outcomes among women affected by herpangina
AU - Chen, Yi Hua
AU - Lin, Hsiu Chen
AU - Lin, Herng Ching
PY - 2010/7
Y1 - 2010/7
N2 - Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.
AB - Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.
KW - adverse pregnancy outcome
KW - herpangina
KW - pregnancy outcome
UR - http://www.scopus.com/inward/record.url?scp=77953916836&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77953916836&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2010.02.025
DO - 10.1016/j.ajog.2010.02.025
M3 - Article
VL - 203
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 1
ER -