Abstract

Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.

Original languageEnglish
JournalAmerican Journal of Obstetrics and Gynecology
Volume203
Issue number1
DOIs
Publication statusPublished - Jul 2010

Fingerprint

Herpangina
Pregnancy Outcome
Pregnant Women
Confidence Intervals
Gestational Age
Surrogate Mothers
Mothers
Small for Gestational Age Infant
Premature Birth
Ambulatory Care
Logistic Models
Regression Analysis
Parturition

Keywords

  • adverse pregnancy outcome
  • herpangina
  • pregnancy outcome

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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title = "Increased risk of adverse pregnancy outcomes among women affected by herpangina",
abstract = "Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95{\%} confidence interval [CI], 1.42-3.69), 1.67- (95{\%} CI, 1.04-2.68), and 1.63-fold (95{\%} CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.",
keywords = "adverse pregnancy outcome, herpangina, pregnancy outcome",
author = "Chen, {Yi Hua} and Lin, {Hsiu Chen} and Lin, {Herng Ching}",
year = "2010",
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doi = "10.1016/j.ajog.2010.02.025",
language = "English",
volume = "203",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
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T1 - Increased risk of adverse pregnancy outcomes among women affected by herpangina

AU - Chen, Yi Hua

AU - Lin, Hsiu Chen

AU - Lin, Herng Ching

PY - 2010/7

Y1 - 2010/7

N2 - Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.

AB - Objective: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. Study Design: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. Results: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. Conclusion: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.

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