Abstract

Introduction The study aimed to explore the frequency and risk of stroke following hospitalization for burn through the analysis of a population-based dataset in Taiwan. Methods We identified 692 hospitalized subjects who had received a diagnosis of burn. We randomly selected 2768 comparison subjects to match the study subjects by sex and age group. We individually tracked each subject for one year identifying all those who received a diagnosis of stroke during that period. Cox proportional hazards regressions were performed to calculate the longitudinal hazard of stroke between the two cohorts. Results We found that the incidence rate of stroke during the one-year follow-up period was 6.65 (95% CI: 4.92-8.79) per 100 person-years and 2.75 (95% CI: 2.18-3.42) per 100 person-years for study cohort and comparison cohort, respectively. After adjusting for urbanization level, monthly income, geographic region, hypertension, diabetes, coronary heart disease, heart failure, atrial fibrillation, hyperlipidemia, and chronic kidney disease, and censoring the cases that died from non-stroke causes, the hazard ratio (HR) for stroke during the one-year follow-up period for study cohort was 2.52 (95% CI = 1.73-3.68, P <0.001) that of comparison subjects. We further analyzed the HR of stroke according to the extent of burned body surface area (29%). We found that there was no significant difference in the risk of stroke during the one-year follow-up period among these three groups of subjects. Conclusions We found that burn victims were at higher risk for subsequent stroke that matched comparison subjects during one-year follow-up.

Original languageEnglish
Pages (from-to)54-60
Number of pages7
JournalBurns
Volume40
Issue number1
DOIs
Publication statusPublished - Feb 2014

Fingerprint

Stroke
Population
Urbanization
Body Surface Area
Hyperlipidemias
Taiwan
Chronic Renal Insufficiency
Atrial Fibrillation
Coronary Disease
Hospitalization
Cohort Studies
Heart Failure
Age Groups
Hypertension
Incidence

Keywords

  • Burn
  • Intensive care
  • Stroke

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine
  • Surgery

Cite this

Increased risk for stroke in burn patients : A population-based one-year follow-up study. / Chung, Shiu Dong; Chen, Chin Shyan; Lin, Herng Ching; Kang, Jiunn Horng.

In: Burns, Vol. 40, No. 1, 02.2014, p. 54-60.

Research output: Contribution to journalArticle

@article{8acaf7c089c9461db3a08cbc07a4f2fd,
title = "Increased risk for stroke in burn patients: A population-based one-year follow-up study",
abstract = "Introduction The study aimed to explore the frequency and risk of stroke following hospitalization for burn through the analysis of a population-based dataset in Taiwan. Methods We identified 692 hospitalized subjects who had received a diagnosis of burn. We randomly selected 2768 comparison subjects to match the study subjects by sex and age group. We individually tracked each subject for one year identifying all those who received a diagnosis of stroke during that period. Cox proportional hazards regressions were performed to calculate the longitudinal hazard of stroke between the two cohorts. Results We found that the incidence rate of stroke during the one-year follow-up period was 6.65 (95{\%} CI: 4.92-8.79) per 100 person-years and 2.75 (95{\%} CI: 2.18-3.42) per 100 person-years for study cohort and comparison cohort, respectively. After adjusting for urbanization level, monthly income, geographic region, hypertension, diabetes, coronary heart disease, heart failure, atrial fibrillation, hyperlipidemia, and chronic kidney disease, and censoring the cases that died from non-stroke causes, the hazard ratio (HR) for stroke during the one-year follow-up period for study cohort was 2.52 (95{\%} CI = 1.73-3.68, P <0.001) that of comparison subjects. We further analyzed the HR of stroke according to the extent of burned body surface area (29{\%}). We found that there was no significant difference in the risk of stroke during the one-year follow-up period among these three groups of subjects. Conclusions We found that burn victims were at higher risk for subsequent stroke that matched comparison subjects during one-year follow-up.",
keywords = "Burn, Intensive care, Stroke",
author = "Chung, {Shiu Dong} and Chen, {Chin Shyan} and Lin, {Herng Ching} and Kang, {Jiunn Horng}",
year = "2014",
month = "2",
doi = "10.1016/j.burns.2013.05.018",
language = "English",
volume = "40",
pages = "54--60",
journal = "Burns",
issn = "0305-4179",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - Increased risk for stroke in burn patients

T2 - A population-based one-year follow-up study

AU - Chung, Shiu Dong

AU - Chen, Chin Shyan

AU - Lin, Herng Ching

AU - Kang, Jiunn Horng

PY - 2014/2

Y1 - 2014/2

N2 - Introduction The study aimed to explore the frequency and risk of stroke following hospitalization for burn through the analysis of a population-based dataset in Taiwan. Methods We identified 692 hospitalized subjects who had received a diagnosis of burn. We randomly selected 2768 comparison subjects to match the study subjects by sex and age group. We individually tracked each subject for one year identifying all those who received a diagnosis of stroke during that period. Cox proportional hazards regressions were performed to calculate the longitudinal hazard of stroke between the two cohorts. Results We found that the incidence rate of stroke during the one-year follow-up period was 6.65 (95% CI: 4.92-8.79) per 100 person-years and 2.75 (95% CI: 2.18-3.42) per 100 person-years for study cohort and comparison cohort, respectively. After adjusting for urbanization level, monthly income, geographic region, hypertension, diabetes, coronary heart disease, heart failure, atrial fibrillation, hyperlipidemia, and chronic kidney disease, and censoring the cases that died from non-stroke causes, the hazard ratio (HR) for stroke during the one-year follow-up period for study cohort was 2.52 (95% CI = 1.73-3.68, P <0.001) that of comparison subjects. We further analyzed the HR of stroke according to the extent of burned body surface area (29%). We found that there was no significant difference in the risk of stroke during the one-year follow-up period among these three groups of subjects. Conclusions We found that burn victims were at higher risk for subsequent stroke that matched comparison subjects during one-year follow-up.

AB - Introduction The study aimed to explore the frequency and risk of stroke following hospitalization for burn through the analysis of a population-based dataset in Taiwan. Methods We identified 692 hospitalized subjects who had received a diagnosis of burn. We randomly selected 2768 comparison subjects to match the study subjects by sex and age group. We individually tracked each subject for one year identifying all those who received a diagnosis of stroke during that period. Cox proportional hazards regressions were performed to calculate the longitudinal hazard of stroke between the two cohorts. Results We found that the incidence rate of stroke during the one-year follow-up period was 6.65 (95% CI: 4.92-8.79) per 100 person-years and 2.75 (95% CI: 2.18-3.42) per 100 person-years for study cohort and comparison cohort, respectively. After adjusting for urbanization level, monthly income, geographic region, hypertension, diabetes, coronary heart disease, heart failure, atrial fibrillation, hyperlipidemia, and chronic kidney disease, and censoring the cases that died from non-stroke causes, the hazard ratio (HR) for stroke during the one-year follow-up period for study cohort was 2.52 (95% CI = 1.73-3.68, P <0.001) that of comparison subjects. We further analyzed the HR of stroke according to the extent of burned body surface area (29%). We found that there was no significant difference in the risk of stroke during the one-year follow-up period among these three groups of subjects. Conclusions We found that burn victims were at higher risk for subsequent stroke that matched comparison subjects during one-year follow-up.

KW - Burn

KW - Intensive care

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=84892609950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892609950&partnerID=8YFLogxK

U2 - 10.1016/j.burns.2013.05.018

DO - 10.1016/j.burns.2013.05.018

M3 - Article

C2 - 23831170

AN - SCOPUS:84892609950

VL - 40

SP - 54

EP - 60

JO - Burns

JF - Burns

SN - 0305-4179

IS - 1

ER -