Incidental Second and Third Primary Cancers Asynchronously Detected by FDG-PET in a Patient with Breast Cancer

Tay Jiunn Lee, Chun-Chao Chang, Chih-Hsiung Wu, Yun-Ho Lin, Yen Kung Chen, Chung-Huei Hsu

Research output: Contribution to journalArticlepeer-review

Abstract

The frequency of double primary cancers synchronously found in an individual has been increasing. However, synchronous or asynchronous triple primary cancers have rarely been reported. A 69-year-old female received an operation for right breast cancer and subsequent chemotherapy in 2001. During the 5-year follow-up period, second and third primary cancers were asynchronously detected by FDG-PET. Lung cancer was identified and surgery was performed in May and June 2003, respectively. Follow-up FDG-PET performed in March 2006 revealed a biologically active (viable) residual tumor in the perihilar region of the right lung. Surprisingly, an additional focal area with increased FDG uptake in the ascending colon was noted. The patient was symptom-free and had a normal serum CEA level. The lesion was proved to be colon cancer, a third primary cancer asynchronously found in this patient. Whole-body FDG-PET is not only an important tool for the early detection of viable residual tumors in patients with malignancy but also early detection of asynchronously developing cancers in other parts of the body.
Translated title of the contribution一位乳癌病患在追蹤期間被氟-18-去氧葡萄糖正子造影發現另外第二種及第三種原發性癌症
Original languageEnglish
Pages (from-to)171-176
Number of pages6
Journal核子醫學雜誌
Volume21
Issue number3
DOIs
Publication statusPublished - 2008

Keywords

  • 三種癌症
  • 氟-18-去氧葡萄糖
  • 正子造影
  • triple cancers
  • FDG-PET
  • asynchronously

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