Incidence and excess mortality of hip fracture in young adults: A nationwide population-based cohort study

Tsai Hsueh Leu, Wei Chun Chang, Jeff Chien Fu Lin, Chi Lo, Wen Miin Liang, Yu Jun Chang, Dann Pyng Shih, Cheng Chun Wu, Chi Fung Cheng, Sy Jye Wei

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20-40 years in a nationwide population database in Taiwan. Methods: Subjects were selected from Taiwan's National Health Insurance Research Database for the period 2001-2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation. Results: The overall annual incidence, mortality, and standardized mortality ratio (SMR) decreased from 7.68 to 7.23 per 100,000, from 1.37 % to 0.94 %, and from 9.06 to 6.71, respectively, from 2001 to 2008. The 1-year, 2-year, 3-year, 5-year, and 10-year mortality rates were 1.28 %, 2.44 %, 3.54 %, 5.32 %, and 10.50 %, respectively for the whole cohort. The 1-year, 2-year, 3-year, 5-year, and 10-year SMRs were 8.33, 7.59, 7.28, 6.39, and 5.82, respectively, for the whole cohort. Risk factors for overall death were male gender, trochanteric fracture, hemiarthroplasty, and higher Charlson comorbidity index (CCI) scores. Conclusions: The high SMRs found in the present study suggest that young adults with former hip fracture should be closely followed up to prevent early mortality.

Original languageEnglish
Article number326
JournalBMC Musculoskeletal Disorders
Volume17
Issue number1
DOIs
Publication statusPublished - Aug 5 2016

Fingerprint

Hip Fractures
Young Adult
Cohort Studies
Mortality
Incidence
Population
Taiwan
Databases
Hemiarthroplasty
National Health Programs
Comorbidity
Inpatients
Research

Keywords

  • Hip fracture
  • Incidence
  • Mortality
  • Nationwide population-based study
  • Standardized mortality ratio
  • Young adults

ASJC Scopus subject areas

  • Rheumatology
  • Orthopedics and Sports Medicine

Cite this

Incidence and excess mortality of hip fracture in young adults : A nationwide population-based cohort study. / Leu, Tsai Hsueh; Chang, Wei Chun; Lin, Jeff Chien Fu; Lo, Chi; Liang, Wen Miin; Chang, Yu Jun; Shih, Dann Pyng; Wu, Cheng Chun; Cheng, Chi Fung; Wei, Sy Jye.

In: BMC Musculoskeletal Disorders, Vol. 17, No. 1, 326, 05.08.2016.

Research output: Contribution to journalArticle

Leu, Tsai Hsueh ; Chang, Wei Chun ; Lin, Jeff Chien Fu ; Lo, Chi ; Liang, Wen Miin ; Chang, Yu Jun ; Shih, Dann Pyng ; Wu, Cheng Chun ; Cheng, Chi Fung ; Wei, Sy Jye. / Incidence and excess mortality of hip fracture in young adults : A nationwide population-based cohort study. In: BMC Musculoskeletal Disorders. 2016 ; Vol. 17, No. 1.
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AU - Lo, Chi

AU - Liang, Wen Miin

AU - Chang, Yu Jun

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AB - Background: This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20-40 years in a nationwide population database in Taiwan. Methods: Subjects were selected from Taiwan's National Health Insurance Research Database for the period 2001-2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation. Results: The overall annual incidence, mortality, and standardized mortality ratio (SMR) decreased from 7.68 to 7.23 per 100,000, from 1.37 % to 0.94 %, and from 9.06 to 6.71, respectively, from 2001 to 2008. The 1-year, 2-year, 3-year, 5-year, and 10-year mortality rates were 1.28 %, 2.44 %, 3.54 %, 5.32 %, and 10.50 %, respectively for the whole cohort. The 1-year, 2-year, 3-year, 5-year, and 10-year SMRs were 8.33, 7.59, 7.28, 6.39, and 5.82, respectively, for the whole cohort. Risk factors for overall death were male gender, trochanteric fracture, hemiarthroplasty, and higher Charlson comorbidity index (CCI) scores. Conclusions: The high SMRs found in the present study suggest that young adults with former hip fracture should be closely followed up to prevent early mortality.

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