Improvement of accidental coincidence estimation for scanditronix PC2048/4096 PET scanners

Chi Hsien Chen, Chin Lung Yu, Liang Chih Wu, Ren Shyan Liu

Research output: Contribution to journalArticle

Abstract

Accidental coincidence (randoms) is one of the factors that degrade the accuracy of positron emission tomography (PET). In contrast to widely-held beliefs, we have previously shown that randoms can significantly affect quantitative PET even after current hardware/software randoms correction is applied. In order to have better estimation of randoms for our Scanditronix scanner, we investigated the limitation of the vendor-provided randoms estimation and proposed a simple modification. Methods: Multiple short-frame data of a homogeneous circular cylinder were collected over 12 hours. Summed data were generated by summing up selected frames. Randoms of the summed data estimated by the vendor-provided method and our modified method were compared. Results: The vendor-provided randoms estimation did not work as well as the modified method when frame duration is much larger than the half-life of the radioactive agent used. Conclusion: Our minimal modification of the vendor-provided method significantly improves randoms estimation.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalJournal of Medical and Biological Engineering
Volume24
Issue number3
Publication statusPublished - Sep 2004

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Positron emission tomography
Positron-Emission Tomography
Circular cylinders
Half-Life
Hardware
Software

Keywords

  • Algorithms
  • Positron emission tomography
  • Scintillation counting

ASJC Scopus subject areas

  • Biophysics

Cite this

Improvement of accidental coincidence estimation for scanditronix PC2048/4096 PET scanners. / Chen, Chi Hsien; Yu, Chin Lung; Wu, Liang Chih; Liu, Ren Shyan.

In: Journal of Medical and Biological Engineering, Vol. 24, No. 3, 09.2004, p. 121-123.

Research output: Contribution to journalArticle

Chen, Chi Hsien ; Yu, Chin Lung ; Wu, Liang Chih ; Liu, Ren Shyan. / Improvement of accidental coincidence estimation for scanditronix PC2048/4096 PET scanners. In: Journal of Medical and Biological Engineering. 2004 ; Vol. 24, No. 3. pp. 121-123.
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