Imported case of malaria in Taiwan: analysis of 11 cases

S. Y. Lin, S. H. Tzeng, Y. M. Chang, C. P. Siauw, P. H. Chen

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The "eradication of malaria" in Taiwan was announced by WHO in 1965. From 1966 to 1989, 919 malaria cases were detected in Taiwan. Of these cases, 803 were classified as imported malaria. During 1977 to 1989, our hospital collected 11 cases of imported malaria, 6 of Plasmodium falciparum (PF), including 1 suspicious case, 2 of Plasmodium vivax (PV), 1 of mixed infection (PF plus PV), and 2 unclassified. Most of the patients presented clinically with fever and chills. Hepatosplenomegaly was the most common abnormal finding during the physical examination. Jaundice and anemia occurred in the more severe cases. No cases had lymphadenopathy which is helpful in making a differential diagnosis. Six cases had thrombocytopenia which may be considered as an indirect sign in the diagnosis. The MCV levels were within normal limits in all of the cases. This may indirectly imply a potential protective effect against malaria infection in cases of congenital hemoglobinopathy such as thalassemia or G6PD deficiency. Initially, 10 cases were given "standard treatment", which consisted of chloroquine 450 mg qd for 2 days then 300 mg qd for 2 days and primaquine 15 mg qd for 2 weeks. Four cases of chloroquine resistance were encountered, all in cases with PF infection. Two cases were grade I delayed type resistance and were successfully treated with Fansidar, tetracycline and quinine. Two cases were grade II resistance and presented clinically as cerebral malaria. Intravenous quinine was given plus Fansidar and tetracycline. The cases were resolved without sequele or recurrence. None of the cases, except for 2, received chemoprophylaxis.(ABSTRACT TRUNCATED AT 250 WORDS)

Original languageEnglish
Pages (from-to)308-311
Number of pages4
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume90
Issue number3
Publication statusPublished - Mar 1991
Externally publishedYes

Fingerprint

Taiwan
Malaria
Plasmodium vivax
Quinine
Chloroquine
Plasmodium falciparum
Tetracycline
Primaquine
Cerebral Malaria
Glucosephosphate Dehydrogenase Deficiency
Hemoglobinopathies
Chills
Thalassemia
Falciparum Malaria
Chemoprevention
Jaundice
Coinfection
Thrombocytopenia
Physical Examination
Anemia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lin, S. Y., Tzeng, S. H., Chang, Y. M., Siauw, C. P., & Chen, P. H. (1991). Imported case of malaria in Taiwan: analysis of 11 cases. Journal of the Formosan Medical Association = Taiwan yi zhi, 90(3), 308-311.

Imported case of malaria in Taiwan : analysis of 11 cases. / Lin, S. Y.; Tzeng, S. H.; Chang, Y. M.; Siauw, C. P.; Chen, P. H.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 90, No. 3, 03.1991, p. 308-311.

Research output: Contribution to journalReview article

Lin, SY, Tzeng, SH, Chang, YM, Siauw, CP & Chen, PH 1991, 'Imported case of malaria in Taiwan: analysis of 11 cases', Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 90, no. 3, pp. 308-311.
Lin, S. Y. ; Tzeng, S. H. ; Chang, Y. M. ; Siauw, C. P. ; Chen, P. H. / Imported case of malaria in Taiwan : analysis of 11 cases. In: Journal of the Formosan Medical Association = Taiwan yi zhi. 1991 ; Vol. 90, No. 3. pp. 308-311.
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