Impact of the number of retrieved oocytes on pregnancy outcome in in vitro fertilization

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3 Citations (Scopus)

Abstract

Objective To evaluate the impact of the number of retrieved oocytes on pregnancy outcome. Materials and Methods We retrospectively examined the cycles of 2491 women undergoing in vitro fertilization therapy at Taipei Medical University (Taipei, Taiwan) from August 1995 to March 2009. We divided them into three groups based on their response rate (where H = high, M = middle, and L = low). We conducted this study to evaluate and compare pregnancy outcome in these three groups. Results The total number of retrieved oocytes had a significantly positive correlation with peak E2 levels, and the number of fertilized oocytes, good quality embryos, and available frozen embryos. The number of retrieved oocytes had a positive correlation with pregnancy rates and a negative correlation with fertilization rates. The implantation and abortion rates among the three groups were essentially the same. Compared to the middle and higher responders, the pregnancy rates for lower responders were significantly lower. The pregnancy rates for middle responders and higher responders were not significantly different. Conclusion The benefits of more retrieved oocytes between the lower and the middle responders were obvious. However, the benefits and risks for retrieving more oocytes for the middle and the higher responders remained controversial.

Original languageEnglish
Pages (from-to)821-825
Number of pages5
JournalTaiwanese Journal of Obstetrics and Gynecology
Volume55
Issue number6
DOIs
Publication statusPublished - Dec 1 2016

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Pregnancy Outcome
Fertilization
Oocytes
Pregnancy Rate
Embryonic Structures
Induced Abortion
Taiwan

Keywords

  • IVF
  • number of retrieved oocytes
  • ovarian response
  • pregnancy outcome

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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title = "Impact of the number of retrieved oocytes on pregnancy outcome in in vitro fertilization",
abstract = "Objective To evaluate the impact of the number of retrieved oocytes on pregnancy outcome. Materials and Methods We retrospectively examined the cycles of 2491 women undergoing in vitro fertilization therapy at Taipei Medical University (Taipei, Taiwan) from August 1995 to March 2009. We divided them into three groups based on their response rate (where H = high, M = middle, and L = low). We conducted this study to evaluate and compare pregnancy outcome in these three groups. Results The total number of retrieved oocytes had a significantly positive correlation with peak E2 levels, and the number of fertilized oocytes, good quality embryos, and available frozen embryos. The number of retrieved oocytes had a positive correlation with pregnancy rates and a negative correlation with fertilization rates. The implantation and abortion rates among the three groups were essentially the same. Compared to the middle and higher responders, the pregnancy rates for lower responders were significantly lower. The pregnancy rates for middle responders and higher responders were not significantly different. Conclusion The benefits of more retrieved oocytes between the lower and the middle responders were obvious. However, the benefits and risks for retrieving more oocytes for the middle and the higher responders remained controversial.",
keywords = "IVF, number of retrieved oocytes, ovarian response, pregnancy outcome",
author = "Ming-I Hsu and Chia-Woei Wang and Chi-Huang Chen and Chii-Ruey Tzeng",
year = "2016",
month = "12",
day = "1",
doi = "10.1016/j.tjog.2015.05.009",
language = "English",
volume = "55",
pages = "821--825",
journal = "Taiwanese Journal of Obstetrics and Gynecology",
issn = "1028-4559",
publisher = "臺灣婦產科醫學會",
number = "6",

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T1 - Impact of the number of retrieved oocytes on pregnancy outcome in in vitro fertilization

AU - Hsu, Ming-I

AU - Wang, Chia-Woei

AU - Chen, Chi-Huang

AU - Tzeng, Chii-Ruey

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Objective To evaluate the impact of the number of retrieved oocytes on pregnancy outcome. Materials and Methods We retrospectively examined the cycles of 2491 women undergoing in vitro fertilization therapy at Taipei Medical University (Taipei, Taiwan) from August 1995 to March 2009. We divided them into three groups based on their response rate (where H = high, M = middle, and L = low). We conducted this study to evaluate and compare pregnancy outcome in these three groups. Results The total number of retrieved oocytes had a significantly positive correlation with peak E2 levels, and the number of fertilized oocytes, good quality embryos, and available frozen embryos. The number of retrieved oocytes had a positive correlation with pregnancy rates and a negative correlation with fertilization rates. The implantation and abortion rates among the three groups were essentially the same. Compared to the middle and higher responders, the pregnancy rates for lower responders were significantly lower. The pregnancy rates for middle responders and higher responders were not significantly different. Conclusion The benefits of more retrieved oocytes between the lower and the middle responders were obvious. However, the benefits and risks for retrieving more oocytes for the middle and the higher responders remained controversial.

AB - Objective To evaluate the impact of the number of retrieved oocytes on pregnancy outcome. Materials and Methods We retrospectively examined the cycles of 2491 women undergoing in vitro fertilization therapy at Taipei Medical University (Taipei, Taiwan) from August 1995 to March 2009. We divided them into three groups based on their response rate (where H = high, M = middle, and L = low). We conducted this study to evaluate and compare pregnancy outcome in these three groups. Results The total number of retrieved oocytes had a significantly positive correlation with peak E2 levels, and the number of fertilized oocytes, good quality embryos, and available frozen embryos. The number of retrieved oocytes had a positive correlation with pregnancy rates and a negative correlation with fertilization rates. The implantation and abortion rates among the three groups were essentially the same. Compared to the middle and higher responders, the pregnancy rates for lower responders were significantly lower. The pregnancy rates for middle responders and higher responders were not significantly different. Conclusion The benefits of more retrieved oocytes between the lower and the middle responders were obvious. However, the benefits and risks for retrieving more oocytes for the middle and the higher responders remained controversial.

KW - IVF

KW - number of retrieved oocytes

KW - ovarian response

KW - pregnancy outcome

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