Impact of submucous myoma on the severity of anemia

Jehn Hsiahn Yang, Mei Jou Chen, Chin Der Chen, Chi Ling Chen, Hong Nerng Ho, Yu Shih Yang

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective: To analyze the impact of the diameter (myoma-φ) and the uterine cavity protruding proportion (protruding %) of the submucous myoma on serum hemoglobin (Hb) level. Design: Retrospective descriptive study. Setting: Tertiary university hospital. Patient(s): Two hundred fifty-nine women with a single submucous myoma. Intervention(s): Transvaginal ultrasound examination and office hysteroscopy. Main Outcome Measure(s): Myoma-φ and protruding % were determined with transvaginal ultrasound scan and office hysteroscopy. Menorrhagic period (months) and serum Hb were recorded within 2 weeks of these examinations. Result(s): Serum Hb negatively correlated with myoma-φ, protruding %, and menorrhagic period. The negative association between serum Hb and protruding % was even more prominent after adjusting for myoma-φ. Multivariate regression analysis revealed that myoma-φ and protruding %, after adjusting for the confounding effect of menorrhagic period, maintained a strongly negative correlation with serum Hb level. When myoma-φ was <2 cm, however, the serum Hb levels were similar regardless of the protruding %. Conclusion(s): For women with a single submucous myoma, myoma-φ and protruding % can determine the serum Hb level significantly . As myoma-φ and protruding % increased, the serum Hb level decreased accordingly.

Original languageEnglish
JournalFertility and Sterility
Volume95
Issue number5
DOIs
Publication statusPublished - Jan 1 2011
Externally publishedYes

Fingerprint

Myoma
Anemia
Hemoglobins
Serum
Hysteroscopy
Tertiary Care Centers
Multivariate Analysis
Retrospective Studies
Regression Analysis
Outcome Assessment (Health Care)

Keywords

  • Anemia
  • intrauterine protruding proportion
  • menorrhagia
  • myoma diameter
  • submucous myoma

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

Cite this

Impact of submucous myoma on the severity of anemia. / Yang, Jehn Hsiahn; Chen, Mei Jou; Chen, Chin Der; Chen, Chi Ling; Ho, Hong Nerng; Yang, Yu Shih.

In: Fertility and Sterility, Vol. 95, No. 5, 01.01.2011.

Research output: Contribution to journalArticle

Yang, Jehn Hsiahn ; Chen, Mei Jou ; Chen, Chin Der ; Chen, Chi Ling ; Ho, Hong Nerng ; Yang, Yu Shih. / Impact of submucous myoma on the severity of anemia. In: Fertility and Sterility. 2011 ; Vol. 95, No. 5.
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