Impact of magnetic resonance imaging versus CT on nasopharyngeal carcinoma

Primary tumor target delineation for radiotherapy

Na Na Chung, Lai Lei Ting, Wei Chung Hsu, Louis Tak Lui, Po Ming Wang

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Background. Our aim was to assess the capacity of CT versus MRI for delineating to the primary tumor extent of nasopharyngeal carcinoma (NPC) in treated patients. Methods. From December 1997 to April 2000, 258 patients with NPC were enrolled. We focused on the primary tumor extension and the discrepancy between CT and MRI. The delineation of tumor invasion was crucial for determination of the gross tumor volume (GTV) before radiation therapy. Results. A total of 104 patients (40.3%) had intracranial infiltration detected by MRI, whereas CT showed negative findings (p = 6.879 × 10 -11). Once the pterygopalatine fossa was involved, the chance of intracranial invasion was increased (96.1%). The detectable percentage of pterygopalatine fossa involvement accompanying intracranial invasion was higher with MRI than with CT (96.1% vs 56.9%). Conclusions. More detailed information about T and N classification of NPC was provided by MRI than by CT, which led to better target delineation for radiotherapy.

Original languageEnglish
Pages (from-to)241-246
Number of pages6
JournalHead and Neck
Volume26
Issue number3
DOIs
Publication statusPublished - Mar 1 2004
Externally publishedYes

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Pterygopalatine Fossa
Radiotherapy
Magnetic Resonance Imaging
Neoplasms
Tumor Burden
Nasopharyngeal carcinoma

Keywords

  • CT
  • MRI
  • Nasopharyngeal carcinoma
  • Radiation therapy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Impact of magnetic resonance imaging versus CT on nasopharyngeal carcinoma : Primary tumor target delineation for radiotherapy. / Chung, Na Na; Ting, Lai Lei; Hsu, Wei Chung; Lui, Louis Tak; Wang, Po Ming.

In: Head and Neck, Vol. 26, No. 3, 01.03.2004, p. 241-246.

Research output: Contribution to journalArticle

Chung, Na Na ; Ting, Lai Lei ; Hsu, Wei Chung ; Lui, Louis Tak ; Wang, Po Ming. / Impact of magnetic resonance imaging versus CT on nasopharyngeal carcinoma : Primary tumor target delineation for radiotherapy. In: Head and Neck. 2004 ; Vol. 26, No. 3. pp. 241-246.
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