Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation

Suresh Allamsetty, Li Wei Lo, Yenn Jiang Lin, Shih Lin Chang, Fa Po Chung, Yu Feng Hu, Chin Yu Lin, Yao Ting Chang, Cheng Hung Chiang, Hung Kai Huang, Chao Shun Chan, Van Bun Dan Do, Chung-Hsing Lin, Sunu Raharjo, Shih Jee Jhuo, Rohit Walia, Shih Ann Chen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Aortic dilatation was frequently observed in patients with atrial fibrillation (AF) and non-pulmonary vein (PV) triggers are important for mapping and ablation of AF. We hypothesized that the aortic encroachment area over left atrium (LA) could contribute to the local substrate characteristics. Methods We studied 32 consecutive patients of AF (age = 57.34 ± 8.07, male = 30), including 26 paroxysmal and 6 persistent AFs. Anatomic relationship between LA and aorta, and electrophysiological characteristics of the encroachment areas were investigated. IRB approval was taken. Results The LA bipolar voltage (mean 0.49 ± 0.26 mV) was lower at aortic encroached area compared to global LA (mean 1.52 ± 0.48 mV) and it was statistically significant (p < 0.001). There was a linear correlation between the voltages of LA and distance from the aorta to the aortic encroachment area of LA (p < 0.001, R = 0.616). Non-PV triggers were observed in 34.37% (n = 11) of total patients. The initiation of AF in aortic encroached area was seen in 45.45% (n = 5) of non-PV trigger and 15.62% of total patients. All the patients were followed up for 6 months and 4 (14.81%) out of 27 patients without trigger at aortic encroached site of LA and 1 (20%) out of 5 patients with trigger at aortic encroached site of LA had recurrence of AF. Conclusion The aorta contributed to low voltages on its encroachment area over the anterior wall of LA. Non-pulmonary vein triggers originating from the aortic encroachment area were found in 15.62% of total patients. Careful evaluation of the anatomical relationship between LA and aorta is important during AF ablation for a better long term outcome.

Original languageEnglish
Pages (from-to)650-655
Number of pages6
JournalInternational Journal of Cardiology
Volume227
DOIs
Publication statusPublished - Jan 15 2017
Externally publishedYes

Fingerprint

Heart Atria
Atrial Fibrillation
Veins
Aorta
Research Ethics Committees
Dilatation
Recurrence

Keywords

  • Aorta
  • Atrial fibrillation
  • Encroachment
  • Left atrium
  • Trigger

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Allamsetty, S., Lo, L. W., Lin, Y. J., Chang, S. L., Chung, F. P., Hu, Y. F., ... Chen, S. A. (2017). Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation. International Journal of Cardiology, 227, 650-655. https://doi.org/10.1016/j.ijcard.2016.10.081

Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation. / Allamsetty, Suresh; Lo, Li Wei; Lin, Yenn Jiang; Chang, Shih Lin; Chung, Fa Po; Hu, Yu Feng; Lin, Chin Yu; Chang, Yao Ting; Chiang, Cheng Hung; Huang, Hung Kai; Chan, Chao Shun; Do, Van Bun Dan; Lin, Chung-Hsing; Raharjo, Sunu; Jhuo, Shih Jee; Walia, Rohit; Chen, Shih Ann.

In: International Journal of Cardiology, Vol. 227, 15.01.2017, p. 650-655.

Research output: Contribution to journalArticle

Allamsetty, S, Lo, LW, Lin, YJ, Chang, SL, Chung, FP, Hu, YF, Lin, CY, Chang, YT, Chiang, CH, Huang, HK, Chan, CS, Do, VBD, Lin, C-H, Raharjo, S, Jhuo, SJ, Walia, R & Chen, SA 2017, 'Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation', International Journal of Cardiology, vol. 227, pp. 650-655. https://doi.org/10.1016/j.ijcard.2016.10.081
Allamsetty, Suresh ; Lo, Li Wei ; Lin, Yenn Jiang ; Chang, Shih Lin ; Chung, Fa Po ; Hu, Yu Feng ; Lin, Chin Yu ; Chang, Yao Ting ; Chiang, Cheng Hung ; Huang, Hung Kai ; Chan, Chao Shun ; Do, Van Bun Dan ; Lin, Chung-Hsing ; Raharjo, Sunu ; Jhuo, Shih Jee ; Walia, Rohit ; Chen, Shih Ann. / Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation. In: International Journal of Cardiology. 2017 ; Vol. 227. pp. 650-655.
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abstract = "Background Aortic dilatation was frequently observed in patients with atrial fibrillation (AF) and non-pulmonary vein (PV) triggers are important for mapping and ablation of AF. We hypothesized that the aortic encroachment area over left atrium (LA) could contribute to the local substrate characteristics. Methods We studied 32 consecutive patients of AF (age = 57.34 ± 8.07, male = 30), including 26 paroxysmal and 6 persistent AFs. Anatomic relationship between LA and aorta, and electrophysiological characteristics of the encroachment areas were investigated. IRB approval was taken. Results The LA bipolar voltage (mean 0.49 ± 0.26 mV) was lower at aortic encroached area compared to global LA (mean 1.52 ± 0.48 mV) and it was statistically significant (p < 0.001). There was a linear correlation between the voltages of LA and distance from the aorta to the aortic encroachment area of LA (p < 0.001, R = 0.616). Non-PV triggers were observed in 34.37{\%} (n = 11) of total patients. The initiation of AF in aortic encroached area was seen in 45.45{\%} (n = 5) of non-PV trigger and 15.62{\%} of total patients. All the patients were followed up for 6 months and 4 (14.81{\%}) out of 27 patients without trigger at aortic encroached site of LA and 1 (20{\%}) out of 5 patients with trigger at aortic encroached site of LA had recurrence of AF. Conclusion The aorta contributed to low voltages on its encroachment area over the anterior wall of LA. Non-pulmonary vein triggers originating from the aortic encroachment area were found in 15.62{\%} of total patients. Careful evaluation of the anatomical relationship between LA and aorta is important during AF ablation for a better long term outcome.",
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T1 - Impact of aortic encroachment to left atrium on non-pulmonary vein triggers of atrial fibrillation

AU - Allamsetty, Suresh

AU - Lo, Li Wei

AU - Lin, Yenn Jiang

AU - Chang, Shih Lin

AU - Chung, Fa Po

AU - Hu, Yu Feng

AU - Lin, Chin Yu

AU - Chang, Yao Ting

AU - Chiang, Cheng Hung

AU - Huang, Hung Kai

AU - Chan, Chao Shun

AU - Do, Van Bun Dan

AU - Lin, Chung-Hsing

AU - Raharjo, Sunu

AU - Jhuo, Shih Jee

AU - Walia, Rohit

AU - Chen, Shih Ann

PY - 2017/1/15

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N2 - Background Aortic dilatation was frequently observed in patients with atrial fibrillation (AF) and non-pulmonary vein (PV) triggers are important for mapping and ablation of AF. We hypothesized that the aortic encroachment area over left atrium (LA) could contribute to the local substrate characteristics. Methods We studied 32 consecutive patients of AF (age = 57.34 ± 8.07, male = 30), including 26 paroxysmal and 6 persistent AFs. Anatomic relationship between LA and aorta, and electrophysiological characteristics of the encroachment areas were investigated. IRB approval was taken. Results The LA bipolar voltage (mean 0.49 ± 0.26 mV) was lower at aortic encroached area compared to global LA (mean 1.52 ± 0.48 mV) and it was statistically significant (p < 0.001). There was a linear correlation between the voltages of LA and distance from the aorta to the aortic encroachment area of LA (p < 0.001, R = 0.616). Non-PV triggers were observed in 34.37% (n = 11) of total patients. The initiation of AF in aortic encroached area was seen in 45.45% (n = 5) of non-PV trigger and 15.62% of total patients. All the patients were followed up for 6 months and 4 (14.81%) out of 27 patients without trigger at aortic encroached site of LA and 1 (20%) out of 5 patients with trigger at aortic encroached site of LA had recurrence of AF. Conclusion The aorta contributed to low voltages on its encroachment area over the anterior wall of LA. Non-pulmonary vein triggers originating from the aortic encroachment area were found in 15.62% of total patients. Careful evaluation of the anatomical relationship between LA and aorta is important during AF ablation for a better long term outcome.

AB - Background Aortic dilatation was frequently observed in patients with atrial fibrillation (AF) and non-pulmonary vein (PV) triggers are important for mapping and ablation of AF. We hypothesized that the aortic encroachment area over left atrium (LA) could contribute to the local substrate characteristics. Methods We studied 32 consecutive patients of AF (age = 57.34 ± 8.07, male = 30), including 26 paroxysmal and 6 persistent AFs. Anatomic relationship between LA and aorta, and electrophysiological characteristics of the encroachment areas were investigated. IRB approval was taken. Results The LA bipolar voltage (mean 0.49 ± 0.26 mV) was lower at aortic encroached area compared to global LA (mean 1.52 ± 0.48 mV) and it was statistically significant (p < 0.001). There was a linear correlation between the voltages of LA and distance from the aorta to the aortic encroachment area of LA (p < 0.001, R = 0.616). Non-PV triggers were observed in 34.37% (n = 11) of total patients. The initiation of AF in aortic encroached area was seen in 45.45% (n = 5) of non-PV trigger and 15.62% of total patients. All the patients were followed up for 6 months and 4 (14.81%) out of 27 patients without trigger at aortic encroached site of LA and 1 (20%) out of 5 patients with trigger at aortic encroached site of LA had recurrence of AF. Conclusion The aorta contributed to low voltages on its encroachment area over the anterior wall of LA. Non-pulmonary vein triggers originating from the aortic encroachment area were found in 15.62% of total patients. Careful evaluation of the anatomical relationship between LA and aorta is important during AF ablation for a better long term outcome.

KW - Aorta

KW - Atrial fibrillation

KW - Encroachment

KW - Left atrium

KW - Trigger

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