Impact of Active Surveillance and Contact Isolation on Transmission of Methicillin-resistant Staphylococcus aureus in Intensive Care Units in an Area With High Prevalence

Jann Tay Wang, Tsai Ling Lauderdale, Wen Sen Lee, Jeng Hua Huang, Tsung Hsi Wang, Shan Chwen Chang

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7 Citations (Scopus)

Abstract

Background/Purpose: Previous research has suggested that active surveillance and early initiation of contact isolation (ASI) can control the nosocomial spread of methicillin-resistant Staphylococcus aureus (MRSA), especially among intensive care unit (ICU) patients. However, these interventions have never been implemented in Taiwan. Methods: This study was conducted from September 2005 to October 2006 to evaluate the effect of ASI on the spread of MRSA in two medical centers in Taiwan with a high prevalence of MRSA. One ICU from each hospital was selected as a study site. In phase I (the first 6 months), only active surveillance was introduced. In phase II (the final 6 months), ASI for patients who had positive MRSA cultures was implemented. Results: The incidence of acquiring MRSA during ICU stay did not differ significantly during phases I and II in hospital A (p = 0.940) and hospital B (p = 0.810). The independent risk factors for acquiring MRSA in the ICU were length of stay and presence of respiratory tract diseases. Conclusion: This study demonstrated that, given the current resource limitations, ASI alone could not reduce MRSA transmission in two ICUs in Taiwan, where the MRSA prevalence was high.

Original languageEnglish
Pages (from-to)258-268
Number of pages11
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume109
Issue number4
DOIs
Publication statusPublished - Apr 2010

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Keywords

  • intensive care units
  • methicillin-resistant Staphylococcus aureus
  • patient isolation
  • surveillance

ASJC Scopus subject areas

  • Medicine(all)

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