Abstract
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P
| Original language | English |
|---|---|
| Article number | 143 |
| Journal | Critical Care |
| Volume | 19 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Apr 8 2015 |
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ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine
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Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost : A quasi-experimental study in surgical intensive care unit. / Lee, Yuarn Jang; Chen, Jen Zon; Lin, Hsiu Chen; Liu, Hsin Yi; Lin, Shyr Yi; Lin, Hsien Ho; Fang, Chi Tai; Hsueh, Po Ren.
In: Critical Care, Vol. 19, No. 1, 143, 08.04.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost
T2 - A quasi-experimental study in surgical intensive care unit
AU - Lee, Yuarn Jang
AU - Chen, Jen Zon
AU - Lin, Hsiu Chen
AU - Liu, Hsin Yi
AU - Lin, Shyr Yi
AU - Lin, Hsien Ho
AU - Fang, Chi Tai
AU - Hsueh, Po Ren
PY - 2015/4/8
Y1 - 2015/4/8
N2 - Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P
AB - Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P
UR - http://www.scopus.com/inward/record.url?scp=84928009467&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928009467&partnerID=8YFLogxK
U2 - 10.1186/s13054-015-0876-y
DO - 10.1186/s13054-015-0876-y
M3 - Article
C2 - 25882709
AN - SCOPUS:84928009467
VL - 19
JO - Critical Care
JF - Critical Care
SN - 1466-609X
IS - 1
M1 - 143
ER -