Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit

Yuarn Jang Lee; Jen Zon Chen; Hsiu Chen Lin; Hsin Yi Liu; Shyr Yi Lin; Hsien Ho Lin; Chi Tai Fang; Po Ren Hsueh

doi:10.1186/s13054-015-0876-y

Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit

Yuarn Jang Lee, Jen Zon Chen, Hsiu Chen Lin, Hsin Yi Liu, Shyr Yi Lin, Hsien Ho Lin, Chi Tai Fang, Po Ren Hsueh

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P

Original language	English
Article number	143
Journal	Critical Care
Volume	19
Issue number	1
DOIs	https://doi.org/10.1186/s13054-015-0876-y
Publication status	Published - Apr 8 2015

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

Access to Document

10.1186/s13054-015-0876-y

Fingerprint

Dive into the research topics of 'Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit'. Together they form a unique fingerprint.

Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: a quasi-experimental study in surgical intensive care unit
Fang, C. (Creator), Liu, H. (Creator), Lin, S. (Creator), Lin, H. (Creator), Lin, H. (Creator), Hsueh, P. (Creator), Lee, Y. (Creator) & Chen, J. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5540209.v1, https://doi.org/10.6084%2Fm9.figshare.c.5540209.v1
Dataset
Additional file 1 of Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: a quasi-experimental study in surgical intensive care unit
Lee, Y. (Creator), Lin, H. (Creator), Lin, S. (Creator), Chen, J. (Creator), Fang, C. (Creator), Liu, H. (Creator), Lin, H. (Creator) & Hsueh, P. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.15095395.v1, https://doi.org/10.6084%2Fm9.figshare.15095395.v1
Dataset

Cite this

Lee, Y. J., Chen, J. Z., Lin, H. C., Liu, H. Y., Lin, S. Y., Lin, H. H., Fang, C. T., & Hsueh, P. R. (2015). Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit. Critical Care, 19(1), [143]. https://doi.org/10.1186/s13054-015-0876-y

Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost : A quasi-experimental study in surgical intensive care unit. / Lee, Yuarn Jang; Chen, Jen Zon; Lin, Hsiu Chen et al.

In: Critical Care, Vol. 19, No. 1, 143, 08.04.2015.

Research output: Contribution to journal › Article › peer-review

Lee, YJ, Chen, JZ, Lin, HC , Liu, HY , Lin, SY, Lin, HH, Fang, CT & Hsueh, PR 2015, 'Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit', Critical Care, vol. 19, no. 1, 143. https://doi.org/10.1186/s13054-015-0876-y

@article{e4a64dbbc79d49ac8dd3c867284d315e,

title = "Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit",

abstract = "Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P ",

author = "Lee, {Yuarn Jang} and Chen, {Jen Zon} and Lin, {Hsiu Chen} and Liu, {Hsin Yi} and Lin, {Shyr Yi} and Lin, {Hsien Ho} and Fang, {Chi Tai} and Hsueh, {Po Ren}",

year = "2015",

month = apr,

day = "8",

doi = "10.1186/s13054-015-0876-y",

language = "English",

volume = "19",

journal = "Critical Care",

issn = "1466-609X",

publisher = "Springer Science + Business Media",

number = "1",

}

TY - JOUR

T1 - Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost

T2 - A quasi-experimental study in surgical intensive care unit

AU - Lee, Yuarn Jang

AU - Chen, Jen Zon

AU - Lin, Hsiu Chen

AU - Liu, Hsin Yi

AU - Lin, Shyr Yi

AU - Lin, Hsien Ho

AU - Fang, Chi Tai

AU - Hsueh, Po Ren

PY - 2015/4/8

Y1 - 2015/4/8

N2 - Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P

AB - Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen of healthcare-associated infections in intensive care units (ICUs). Prior studies have shown that decolonization of MRSA carriers is an effective method to reduce MRSA infections in ICU patients. However, there is currently a lack of data on its effect on mortality and medical cost. Methods: Using a quasi-experimental, interrupted time-series design with re-introduction of intervention, we evaluated the impact of active screening and decolonization on MRSA infections, mortality and medical costs in the surgical ICU of a university hospital in Taiwan. Regression models were used to adjust for effects of confounding variables. Results: MRSA infection rate decreased from 3.58 (baseline) to 0.42‰ (intervention period) (P

UR - http://www.scopus.com/inward/record.url?scp=84928009467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928009467&partnerID=8YFLogxK

U2 - 10.1186/s13054-015-0876-y

DO - 10.1186/s13054-015-0876-y

M3 - Article

C2 - 25882709

AN - SCOPUS:84928009467

VL - 19

JO - Critical Care

JF - Critical Care

SN - 1466-609X

IS - 1

M1 - 143

ER -

Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: A quasi-experimental study in surgical intensive care unit

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Datasets

Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: a quasi-experimental study in surgical intensive care unit

Additional file 1 of Impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) and decolonization on MRSA infections, mortality and medical cost: a quasi-experimental study in surgical intensive care unit

Cite this