Immunohistochemical analyses of p53 protein expression in breast cancers in Taiwan: A clinicopathologic study

Jan Show Chu, Wei Jei Lee, King Jen Chang, Hey Chi Hsu

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Immunohistochemical analysis of the p53 protein was performed on paraffin sections of tumor tissue from 210 breast cancer patients. All patients had a follow-up period of more than 5 years. Protein expression of p53 was detected in 64 patients (30.5%). There was significant correlation between p53 protein expression and a high histologic grade (grade III vs grade I/II, 49% vs 23.6%, p = 0.0008) and high mitotic index (≤10/10 hpf vs

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume96
Issue number4
Publication statusPublished - Apr 1997
Externally publishedYes

Keywords

  • breast cancer
  • immunohistochemistry
  • p53 protein expression
  • protein expression

ASJC Scopus subject areas

  • Medicine(all)

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