Ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose calcium polystyrene sulfonate

Chih Chin Kao, Yi Chiun Tsai, Wen Chih Chiang, Tsui Lien Mao, Tze Wah Kao

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A rare but severe complication, intestinal necrosis, has been reported after sodium polystyrene sulfonate (SPS; Kayexalate) and sorbitol intake. Some case reports described bowel perforation following calcium polystyrene sulfonate (CPS; Kalimate) administration. We report a case of ileum and colon perforation following peritoneal dialysis-related peritonitis and high-dose Kalimate in a 59-year-old female patient. The patient had a history of hypertension, diabetes mellitus, and end-stage renal disease (ESRD). During hospitalization for peritoneal dialysis-related peritonitis, she developed hyperkalemia, and Kalimate was administered orally. However, severe abdominal distension and pain occurred just one day after Kalimate intake. An urgent surgery disclosed several perforations in the ileum and sigmoid colon. Pathology of the resected gut showed transmural necrosis and perforation with basophilic angulated crystals. The patient finally expired during hospitalization due to refractory septic shock.

Original languageEnglish
Article number863
Pages (from-to)1008-1010
Number of pages3
JournalJournal of the Formosan Medical Association
Volume114
Issue number10
DOIs
Publication statusPublished - Oct 1 2015

Keywords

  • Bowel/intestinal perforation
  • End-stage renal disease
  • Kalimate

ASJC Scopus subject areas

  • Medicine(all)

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